grant

Brain Age in Aphasia

Organization UNIVERSITY OF SOUTH CAROLINA AT COLUMBIALocation COLUMBIA, UNITED STATESPosted 1 Sept 2024Deadline 31 Aug 2029
NIHUS FederalResearch GrantFY2025AccelerationAccountingAcquired brain injuryAffectAgeAgingAlogiaAnatomic SitesAnatomic structuresAnatomyAnepiaAphasiaApoplexyAreaAtrophicAtrophyBehavioralBody TissuesBrainBrain InjuriesBrain Nervous SystemBrain Vascular AccidentBrain regionCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCharacteristicsChronicChronologyClinicalCognitionCognitiveCommunicationCompensationDataData BasesData SetDatabasesDiabetes MellitusEducationEducational BackgroundEducational aspectsElderlyElementsEncephalonFunctional MRIFunctional Magnetic Resonance ImagingGeneral PopulationGeneral PublicHabitsHypertensionIndividualInjuryInjury compensationInterdisciplinary ResearchInterdisciplinary StudyKnowledgeLanguageLanguage DisordersLesionLinguisticLinguisticsLinkLogagnosiaLogamnesiaLogastheniaLong-term cohortLongitudinal cohortMachine LearningMeasurableMeasuresMediationMental DepressionMethodsModelingMultidisciplinary CollaborationMultidisciplinary ResearchMultilingualismNegotiatingNegotiationNeurologyNeurosciencesOutcomePersonsPositionPositioning AttributePredispositionPublic HealthPublishingQOLQuality of lifeRecoveryResearchResidualResidual stateRiskSeveritiesSocial isolationSouth CarolinaStreamStrokeStructureSusceptibilitySymptomsSystemTestingTissuesTreatment outcomeUniversitiesVascular Hypertensive DiseaseVascular Hypertensive Disorderadvanced ageafter strokeage associatedage associated neurodegenerationage associated neurodegenerative diseaseage associated neurodegenerative disorderage correlatedage dependentage dependent neurodegenerationage dependent neurodegenerative conditionage dependent neurodegenerative diseaseage dependent neurodegenerative disorderage linkedage relatedage related neurodegenerationage specificage-driven neurodegenerative disordersage-related neurodegenerative diseaseage-related neurodegenerative disorderaged brainagesaging associated neurodegenerationaging associated neurodegenerative diseaseaging brainaging related neurodegenerationaging related neurodegenerative diseaseaging related neurodegenerative disorderaphasia due to strokeaphasia following strokeaphasia recoverybrain atrophybrain attackbrain basedbrain damagebrain tissuebrain-injuredcardiovascular riskcardiovascular risk factorcerebral atrophycerebral vascular accidentcerebrovascular accidentchronic strokecognitive decline after strokecognitive decline in strokecognitive dysfunction after strokecognitive dysfunction in strokecognitive impairment after strokecognitive impairment in strokecohortconnectomecortical atrophydata basedepressiondiabetesfMRIgeriatrichealthy aginghealthy human aginghigh blood pressurehyperpiesiahyperpiesishypertensive diseasehypertensive disorderimprovedin vivoinjuriesinnovateinnovationinnovativeinsightlanguage abilitylanguage deficitlanguage impairmentlanguage processinglanguage skillsmachine based learningmulti-modal neuro-imagingmulti-modalitymultilingualmultimodal neuroimagingmultimodalityneural imagingneuro-imagingneuroimagingneurological imagingnon-speakingnon-verbalnon-vocalnovelpost strokepost stroke cognitive declinepost stroke cognitive dysfunctionpost stroke cognitive impairmentpoststrokepoststroke aphasiapoststroke cognitive declinepoststroke cognitive dysfunctionpoststroke cognitive impairmentprematureprematuritypreventpreventingprospectiveprotective effectrecovery in aphasiarecovery in patients with aphasiarecovery in people with aphasiarecovery of people with aphasiarecruitresilienceresilientsenior citizensocialstroke aphasiastroke survivorstroke survivor with aphasiastroke-induced aphasiastrokedstrokes
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Abstract
Post-stroke chronic aphasia is a prevalent language processing problem commonly associated with

significantly reduced quality of life. Unfortunately, our knowledge of the personalized factors underlying

aphasia severity remains incomplete, and only 50% of the variance can be explained by comprehensive

models that incorporate lesion…

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