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BLR&D Research Career Scientist Award
Organization RLR VA MEDICAL CENTERLocation INDIANAPOLIS, UNITED STATESPosted 1 Apr 2019Deadline 31 Mar 2026 ⚠️
VANIHUS FederalResearch GrantFY20253'5'-cyclic ester of AMP5-HT5-Hydroxytryptamine5HTAdenosine Cyclic 3',5'-MonophosphateAdenosine Cyclic MonophosphateAdenosine, cyclic 3',5'-(hydrogen phosphate)AlcoholicAlcoholic Liver DiseasesAngiogenesis FactorAngiogenic FactorAreaAutocrine SystemsAutoregulationAwardBasic ResearchBasic ScienceBile Duct EpitheliumBile Duct ObstructionBile TractBiliaryBiliary StasisBiliary SystemBiliary TreeBlood SerumBoozerCalcitonin Gene-Related PeptideCell AgingCell BodyCell Communication and SignalingCell SenescenceCell SignalingCellsCellular AgingCellular SenescenceCholangiocarcinomaCholangiocellular CarcinomaCholestasisChronicChronic Non-Suppurative Destructive CholangitisChronic Nonsuppurative Destructive CholangitisClinicalClinical SciencesCollaborationsCyclic AMPDataDependent drinkerDevelopmentDiagnosisDiseaseDisease ProgressionDisorderDrug TherapyDrugsDuctal CellDuctal Epithelial CellEducational process of instructingEnteramineEpithelial CellsEuler-Gaddum Substance PFacultyFatty AlcoholsFatty LiverFibrosisFoundationsFundingGastroenterologyGastrointestinal DiseasesGeneralized GrowthGenesGoalsGrantGrant ReviewGrowthHealthHepatic CirrhosisHepatic DisorderHepatic FailureHepatic Stellate CellHepatic TransplantationHepatobiliaryHepatologyHeterogeneityHippophaineHomeostasisHumanIn VitroInflammationInjury to LiverIntracellular Communication and SignalingInvestigationInvestigatorsIto CellJournalsLiver CirrhosisLiver FailureLiver FibrosisLiver GraftingLiver SteatosisLiver TransplantLiver diseasesMD studentsMagazineMediatingMedicalMedical StudentsMedical centerMedicationMelatoninMentorsMicroRNAsModelingModern ManMolecularNAFLDNASHNational Institutes of HealthNatureNeoplastic Cell TransformationNerve Transmitter SubstancesNeuroendocrineNeuroendocrine SystemNeuropeptidesNeurosecretory SystemsNeurotransmittersPancreatic Secretin ReceptorPathogenesisPathway interactionsPatientsPharmaceutical PreparationsPharmacological TreatmentPharmacotherapyPhenotypePhysiological HomeostasisPlayPopulationPostdocPostdoctoral FellowPreventionPrimary biliary cholangitisPrimary biliary cirrhosisProductivityProgenitor CellsProgram DevelopmentProliferatingPublicationsPublishingReactionReceptor ProteinRegulationReplicative SenescenceResearchResearch AssociateResearch PersonnelResearchersRodentRodent ModelRodentiaRodents MammalsRoleSamplingScientific PublicationScientistSecretinSeminalSensorySerotoninSerumServicesSignal PathwaySignal TransductionSignal Transduction SystemsSignalingSubstance PTeachingTherapeutic AgentsTherapeutic InterventionTissue GrowthTrainingUnited States National Institutes of HealthVeteransViraladenosine 3'5' monophosphateafferent nervealcohol induced hepatic injuryalcohol induced liver disorderalcohol induced liver injuryalcohol related liver diseasealcohol-associated liver diseasealcohol-induced hepatic dysfunctionalcohol-induced liver diseasealcohol-induced liver dysfunctionalcohol-mediated liver dysfunctionalcohol-mediated liver injuryalcohol-related liver diseasealcoholic liver injuryautocrinebile ductbile duct epitheliabile duct epithelialbile ductulebile obstructionbile occlusionbiliary cancerbiliary tractbiological signal transductioncAMPcareercholangiocytecholangiosarcomacholestatic diseasescholestatic disordercholestatic liver diseasecholestatic liver disordercholestatic syndromeschronic hepatic diseasechronic hepatic disorderchronic liver diseasechronic liver disorderclinical relevanceclinically relevantconferenceconventiondevelop therapydevelopmentaldrug interventiondrug treatmentdrug/agenteditorialend stage liver diseaseend stage liver failureethanol induced hepatic injuryethanol induced liver disorderethanol induced liver injuryethanol liver diseaseethanol-induced hepatic dysfunctionethanol-induced liver diseaseethanol-induced liver dysfunctionethanol-mediated liver dysfunctionethanol-mediated liver injuryfibrotic livergastrointestinal disordergraduate studenthepatic damagehepatic diseasehepatic fibrosishepatic injuryhepatic steatosishepatopathyhepatosteatosisin vivoinjury to tissueintervention developmentintervention therapyknowledge translationliver damageliver disorderliver injuryliver transplantationmedical school studentsmeetingmeetingsmembermiRNAneoplastic transformationneuroendocrine phenotypeneurokinin 1non-alcohol fatty liver diseasenon-alcohol induced steatohepatitisnon-alcoholic fatty liver diseasenon-alcoholic liver diseasenon-alcoholic steato-hepatitisnon-alcoholic steatohepatitisnonalcoholic fatty liver diseasenonalcoholic steato-hepatitisnonalcoholic steatohepatitisnovelontogenyparacrinepathwaypeptide Ppeptide P glycosylasepharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticspost-docpost-doctoralpost-doctoral traineeprimary sclerosing cholangitisproblem drinkerprognostic toolprogramsreceptorrepairrepairedreplicative agingresearch associatesresponsesecretin receptorsenescencesenescence and its associated secretory phenotypesenescence associated secretomesenescence associated secretory factorssenescence associated secretory pathwaysenescence associated secretory phenotypesenescence associated secretory programsenescence associated secretory proteinssenescentsenescent associated secretomesenescent associated secretory phenotypesensory nervesocial rolestem cellssummitsymposiasymposiumtherapeutic agent developmenttherapeutic developmenttherapeutically effectivetherapy developmenttissue injurytreatment development
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Description preview
Bile duct epithelial cells (i.e., cholangiocytes) are the target cells in cholangiopathies such as primary biliary
cholangitis (PBC), primary sclerosing cholangitis (PSC), and cholangiocarcinoma (CCA), which are
diseases characterized by the damage, proliferation and neoplastic transformation of cholangiocytes.
These cholestatic liver diseases…
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