grant
Bioinformatics Analysis of Next Generation Sequencing Data from Cancer Cells
Organization NORTHWESTERN UNIVERSITYLocation CHICAGO, UNITED STATESPosted 19 Sept 2017Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY2025AIDSAcquired Immune DeficiencyAcquired Immune Deficiency SyndromeAcquired Immunodeficiency SyndromeAreaAssayAwardBase SequenceBig DataBigDataBioassayBioinformaticsBiological AssayBiologyCancer CenterCancer PatientCancer Research ProgramsCancer Research ProjectCancersCell Culture TechniquesCell FunctionCell PhysiologyCell ProcessCellular FunctionCellular PhysiologyCellular ProcessCenter Core GrantsChromatinComprehensive Cancer CenterComputer AnalysisDNA mutationDataData Science CoreData Science Resource CoreData SetDefectDevelopmentDysfunctionEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessFunctional disorderFundingGene ActivationGene TranscriptionGenetic ChangeGenetic TranscriptionGenetic defectGenetic mutationGoalsGrantHHV-8HHV8HumanHuman Herpesvirus 8InvestigationInvestigatorsKSHVKaposi SarcomaKaposi Sarcoma-Associated Herpes VirusKaposi Sarcoma-Associated HerpesvirusKaposi sarcoma associated virusKaposi sarcoma herpes virusKaposi's SarcomaKaposi's sarcoma (KS)-associated herpesvirusMalignant CellMalignant NeoplasmsMalignant TumorModern ManMolecular Dynamics SimulationMultiple Hemorrhagic SarcomaMutationNGS MethodNGS systemNucleotide SequenceP30 AwardP30 GrantP30 MechanismP30 ProgramPatientsPharmaceutical AgentPharmaceuticalsPharmacologic SubstancePharmacological SubstancePhysiopathologyRNA ExpressionRegulationReproducibilityResearchResearch PersonnelResearchersRoleSubcellular ProcessToxic effectToxicitiesTranscriptionTranscription ElongationUniversitiesVirus-HHV8Workcancer cellcell culturecell culturescomputational analysescomputational analysiscomputer analysesdevelopmentalepigeneticallygenome mutationhigh standardimproved outcomeinsightkaposi's sarcoma herpesviruskaposi's sarcoma-associated human herpesvirusmalignancymembermolecular dynamicsneoplasm/cancernext gen sequencingnext generation sequencingnextgen sequencingnucleic acid sequencepathophysiologypharmaceuticalprogramssocial role
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Project Summary
This proposal is a renewal of a prior R50 grant that supported the bioinformatics needs of cancer
researchers at Northwestern University. The initial award primarily supported two NCI funded
Outstanding Investigators, Dr. Marcus Peter and Dr. Ali Shilatifard, with a small fraction of support for the
Robert H. Lurie Comprehensive…
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