grant
Automated Smart Nerve Stimulator to Assess Neuromechanical Function in Veterans
Organization PHILADELPHIA VA MEDICAL CENTERLocation PHILADELPHIA, UNITED STATESPosted 1 Apr 2026Deadline 31 Mar 2030
VANIHUS FederalResearch GrantFY2026AddressAfter CareAfter-TreatmentAftercareAgeAge YearsArchitectureArthroplastyBiological MarkersBiomechanicsClinicalClinical EvaluationClinical ResearchClinical StudyClinical TestingComplexComputer Software ToolsComputer softwareContracting OpportunitiesContractsCross-Sectional StudiesCross-Sectional SurveyCustomDataData BasesData SetDatabasesDegenerative ArthritisDegenerative polyarthritisDevice or Instrument DevelopmentDiagnosisDiseaseDisease Frequency SurveysDisorderE-stimElectric StimulationElectrodesEngineering / ArchitectureEquipmentEvaluationFutureGastrocnemius MuscleH-ReflexHealthHistoryHydrogelsIntellectual PropertyInvestigatorsJoint Prosthesis ImplantationKneeKnee OsteoarthritisKnee arthroplastyKnee joint replacement operationKnee replacementLearningLocationLower ExtremityLower LimbMachine LearningManualsMeasurementMeasuresMedical centerMedulla SpinalisMembrum inferiusMethodologyMethodsMotionMotorMotor CellMotor NeuronsMuscleMuscle TissueMuscle functionNerveNerve ConductionNeural ConductionNeuromechanicsOperative ProceduresOperative Surgical ProceduresOsteoarthritisOsteoarthrosisOutcomePainPainfulPathologyPatient Outcomes AssessmentsPatient Reported MeasuresPatient Reported OutcomesPatientsPennsylvaniaPerformancePhysiologic pulseProceduresProtocolProtocols documentationPulseQOLQualifyingQuality of lifeRecording of previous eventsReflexReflex actionReplacement ArthroplastyReportingResearchResearch DesignResearch PersonnelResearchersScheduleSeveritiesSocial Support SystemSoftwareSoftware ToolsSpinalSpinal CordStudy TypeSupport SystemSurgicalSurgical InterventionsSurgical ProcedureSymptomsSystemTechnologyTestingTherapeuticTimeTotal Knee ReplacementTrainingTranslationsUniversitiesVeteransWorkagesalleviate symptomameliorating symptombio-markersbiologic markerbiomarkerbiomechanicalclinical testcommercializationcross-sectional research studycustomsdata basedecrease symptomdegenerative joint diseasedensitydesigndesigningdevelop softwaredeveloping computer softwaredevice developmentelectrostimulationextremity injuryextremity traumafewer symptomsgastrocnemiushistorieshypertrophic arthritisimprovedindexinginjury to extremityinnovateinnovationinnovativeinnovative technologiesinstrument developmentinvestigator trainingiterative designjoint arthroplastyjoint replacementknee OAknee joint OAknee joint osteoarthritisknee painknee replacement arthroplastylimb injurylimb traumamachine based learningmachine learned algorithmmachine learning algorithmmachine learning based algorithmmotoneuronmultidisciplinarymuscularnerve damageneuralneuromechanicalnew markernovelnovel biomarkernovel markerpain reductionpost treatmentprototyperecruitreduce painreduce symptomsrelieves symptomsresearch clinical testingresearch studyresponsesensorsexsoftware developmentsoftware toolkitspinal reflexstandard of carestudy designsurgerysymptom alleviationsymptom reductionsymptom relieftechnology platformtechnology systemtooltotal knee arthroplastytranslation
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ABSTRACT
Significance to VA: Knee osteoarthritis is a major health problem in Veterans and accounts for
approximately one-half of all joint replacement surgeries in the VA system. Total knee arthroplasty is the
current standard of care to treat advanced knee osteoarthritis and is effective in reducing pain. However, nearly
1 in 4 patients report…
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