grant
Applications of Lesion-Deficit Mapping to Unresolved Problems in Aphasia
Organization MEDICAL COLLEGE OF WISCONSINLocation MILWAUKEE, UNITED STATESPosted 1 Feb 2026Deadline 31 Jan 2031
NIHUS FederalResearch GrantFY2026AI language modelsAcquired brain injuryAcuteAddressAffectAlogiaAnepiaAnteriorAphasiaApoplexyAreaBehavioralBoatBrainBrain InjuriesBrain Nervous SystemBrain Vascular AccidentCanine SpeciesCanis familiarisCausalityCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeChronicComplementComplement ProteinsComprehensionCoupledDataDevelopmentDiseaseDisorderDogsDogs MammalsEncephalonEtiologyGoalsHeadImpairmentIndividualInferiorKnowledgeLanguageLanguage DisordersLanguage TestsLeftLesionLinguisticLinguisticsLinkLiteratureLocationLogagnosiaLogamnesiaLogastheniaMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMapsMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMethodologyMethodsMiddle Inferior Frontal ConvolutionMiddle Temporal GyrusModelingModernizationNMR ImagingNMR TomographyNamesNeurobiologyNuclear Magnetic Resonance ImagingOperative ProceduresOperative Surgical ProceduresParietal LobePars TriangularisPatternPersonsProcessProductionPsycholinguisticsReaction TimeRefractoryResponse LatenciesResponse RTResponse TimeRetrievalSamplingSemanticsStrokeStructure of middle temporal gyrusSurgicalSurgical InterventionsSurgical ProcedureSymptomsSyndromeTemporal LobeTestingTimeTransformer language modelWord ProcessingWorkZeugmatographyafter strokeangular gyrusaphasia rehabilitationartificial intelligence language modelsbehavior measurementbehavioral measurebehavioral measurementbrain attackbrain damagebrain surgerybrain-injuredcaninecausationcerebral vascular accidentcerebrovascular accidentclinical significanceclinically significantcomplementationcomputer based predictiondesigndesigningdevelopmentaldisease causationdomestic dogfeasibility testingfocal brain damageimprovedlanguage abilitylanguage deficitlanguage impairmentlanguage processinglanguage skillslarge language modellarge scale language modellexicallexical processinglexical retrievallong-term recoverymassive scale language modelsnamenamednamingneuralneural correlateneural imagingneuro-imagingneurobiologicalneuroimagingneurological imagingnon-speakingnon-verbalnon-vocalnoveloutcome predictionparietal cortexpersonal narrativesphonologyphrasespost strokepoststrokepredictive modelingpredictive toolspreservationprocessing speedpsychomotor reaction timerehab strategyrehabilitation strategystroke recoverystrokedstrokessurgerytemporal cortextemporal measurementtemporal resolutiontheoriestime measurementtool
Description preview
PROJECT SUMMARY
A detailed model of how focal damage to the brain affects long-term language abilities would be of enormous
value to clinicians trying to minimize language deficits from brain surgery or predict long-term recovery from
strokes. The principal tool for creating such a model is lesion-deficit mapping (LDM), which generates statistical…
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