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Antibiotic Allergy: Phenotypes, Endotypes, and Mechanisms
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PROJECT SUMMARY
Drug allergy is the leading cause of fatal anaphylaxis in the US, with antibiotics being the most common cause
of allergic reactions. For immediate penicillin allergy, evidence supports specific antigenic determinants and an
immunoglobulin (lg)E-mediated mechanism. For other antibiotics, the antigenic determinants and mechanismsβ¦
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