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Analgesic-Behavioral and Neurophysiological Correlates of Opioid-Sparing Spinal Anesthesia Compared to General Anesthesia in Human Infants

Organization ALBERT EINSTEIN COLLEGE OF MEDICINELocation BRONX, UNITED STATESPosted 1 Jul 2023Deadline 6 Jan 2026 ⚠️
NIHUS FederalResearch GrantFY20250-11 years old21+ years oldAbsence of pain sensationAbsence of sensibility to painAcuteAddressAdultAdult HumanAgeAnalgesic AgentsAnalgesic DrugsAnalgesic PreparationAnalgesicsAnesthesiaAnesthesia proceduresAnesthestic DrugsAnesthetic AgentsAnesthetic DrugsAnestheticsAnodynesAntinociceptive AgentsAntinociceptive DrugsAwarenessBehavior assessmentBehavioralBrainBrain Nervous SystemCareer Development AwardsCareer Development Awards and ProgramsCareer Development Programs K-SeriesCaringChildChild Behavior ChecklistChild Behavioral ChecklistChild YouthChildhoodChildhood Behavior ChecklistChildren (0-21)Children Behavior ChecklistClinicalClinical ResearchClinical StudyCognitionCommunitiesComplexCryingDataData AnalysesData AnalysisData ScienceData SetDedicationsDeliriumDependenceDevelopmentDissociationEEGElectroencephalogramElectroencephalographyEncephalonEnvironmentExhibitsExposure toFaceFeels no painFrequenciesFundingGeneral AnesthesiaGeneral AnestheticsGeneral anesthetic drugsGoalsHourHumanInfantIntensive CareInvestigatorsK-AwardsK-Series Research Career ProgramsK23 AwardK23 MechanismK23 ProgramKnowledgeLegLong-Term EffectsMeasuresMedicalMentored Patient-Oriented Research Career Development AwardMentored Patient-Oriented Research Career Development Award (K23)MentorsMentorshipMissionModalityModern ManMotor SkillsNIDANational Institute of Drug AbuseNational Institute on Drug AbuseNeurologicNeurologicalNeurosciencesNo sensitivity to painOperative ProceduresOperative Surgical ProceduresOpiatesOpioidPainPain ControlPain TherapyPain managementPainfulPhysiciansPhysiologicPhysiologicalPhysiologyPositionPositioning AttributePostoperativePostoperative PeriodPropertyR-Series Research ProjectsR01 MechanismR01 ProgramRegimenReproducibilityResearchResearch Career ProgramResearch DesignResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearch TrainingResearchersRiskSample SizeSedation procedureSleepSpinalSpinal AnesthesiaStudy TypeSubstance abuse problemSurgicalSurgical InterventionsSurgical ProcedureTimeTrainingTraining ActivityUnited StatesWorkabuse of substancesadulthoodagesanalgesiabehavior measurementbehavior outcomebehavioral assessmentbehavioral measurebehavioral measurementbehavioral outcomebrain behaviorcareer developmentdata interpretationdeliriousdesigndesigningdevelopmentalearly life exposureexperiencefacesfacialfollow up assessmentfollowup assessmenthigh riskhypnoticimprovedirritationkidsmotor abilitymotor behaviorneuralneurophysiologicalneurophysiologyopiate consumptionopiate crisisopiate drug useopiate exposureopiate intakeopiate useopioid consumptionopioid crisisopioid drug useopioid epidemicopioid exposureopioid intakeopioid sparingopioid usepain interventionpain killerpain medicationpain relieverpain scorepain treatmentpainkillerpediatricprospectiverecruitrisk minimizationsedationsedativeskillssleep spindlespinal blockstudy designsubstance abusesubstance misusesurgerytraining moduleyoungster

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Description preview

Each year, approximately 6 million children receive anesthesia in the United States alone. The ongoing opioid epidemic has forced the medical community to examine how it uses opioids for pain management. There is now evidence that early life exposure to opioids is associated with greater sensitivity to pain, adverse long-term effects on…

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