grant

An implementation science approach to the design and evaluation of tuberculosis self-testing

Organization JOHNS HOPKINS UNIVERSITYLocation BALTIMORE, UNITED STATESPosted 11 Sept 2023Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY2025AIDS VirusAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAddressAdoptedAgeAssess implementationBaltimoreBiological TestingCaringCommunitiesDataDetectionDevelopmentDiagnosisDiagnostic testsDiseaseDisorderEffectivenessEvaluationFutureGoalsGrantHIVHealthHouseholdHuman Immunodeficiency VirusesImplementation assessmentIndividualInterventionInterviewLAV-HTLV-IIILaboratoriesLymphadenopathy-Associated VirusM tuberculosis infectionM. tb infectionM. tuberculosis infectionM.tb infectionM.tuberculosis infectionMTB infectionMaintenanceMethodsMolecularMycobacterium tuberculosis (MTB) infectionMycobacterium tuberculosis infectionOralOutcomePatientsPersonsPositionPositioning AttributeProspective StudiesResearchResearch DesignResearch MethodologyResearch MethodsResearch SpecimenRiskSelf AssessmentShippingSpecimenStudy TypeSurvey InstrumentSurveysSwabTB diagnosticsTB infectionTest ResultTestingTrainingTuberculosisVirus-HIVVulnerable Populationsagesassess effectivenessbarriers to implementationburden to communitycare seekingcase findingcommunicable disease diagnosiscommunity burdencommunity settingcostdesigndesigningdetermine effectivenessdevelopmentaldiagnostic assaydiagnostic technologiesdiagnostic tooldisseminated TBdisseminated tuberculosiseffectiveness assessmenteffectiveness evaluationeffectiveness/implementation hybrid studyeffectiveness/implementation studyevaluate effectivenessevaluate implementationevaluation of implementationexamine effectivenessglobal healthimplementation barriersimplementation challengesimplementation evaluationimplementation scienceimprovedinfection due to Mycobacterium tuberculosisinfectious disease diagnosisinnovateinnovationinnovativepatient centeredpatient orientedpragmatic studyprimary outcomepublic health relevanceresearch and methodsself testingskillsstudy designtooltuberculosis diagnosticstuberculosis infectiontuberculous spondyloarthropathyvulnerable groupvulnerable individualvulnerable people
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Tuberculosis (TB) remains a major global health crisis, causing 10 million new cases in 2023. Despite extensive efforts by the global community to identify TB cases, 30% of new cases went undiagnosed. Current strategies focus on active case finding, which is costly and hard to implement practically. One potential solution to these challenges is…

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An implementation science approach to the design and evaluation of tuberculosis self-testing — JOHNS HOPKINS UNIVERSITY | Dev Procure