grant
Adapting Machine Learning Approaches to Identify a Robust Measure and Key Risk and Protective Factors of Change in Allostatic Load across the Adult Lifespan
Organization UNIVERSITY OF FLORIDALocation GAINESVILLE, UNITED STATESPosted 1 Sept 2025Deadline 31 May 2030
NIHUS FederalResearch GrantFY202512-20 years old21+ years oldAD related dementiaADRDAdd HealthAddressAdolescenceAdolescentAdolescent YouthAdultAdult HumanAffectAgeAgingAlgorithmsAlzheimer's and related dementiasAlzheimer's dementia and related dementiaAlzheimer's dementia or related dementiaAlzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementiaAlzheimer's disease related dementiaAmentiaAutomobile DrivingBehavioralBiologicalBiological FunctionBiological MarkersBiological ProcessBiosocialBlack PopulationsBlack groupBlack individualBlack peopleBlacksCardiac DiseasesCardiac DisordersCardiovascularCardiovascular Body SystemCardiovascular DiseasesCardiovascular Organ SystemCardiovascular systemCausalityCell Communication and SignalingCell SignalingChronic DiseaseChronic IllnessChronic stressClinicalCollectionComplexConsensusDNA MethylationDataData ScienceData SetDecrease health disparitiesDementiaDevelopmentDiabetes MellitusDimensionsDiseaseDisorderDisparitiesDisparityEarly DiagnosisEarly InterventionEducationEducational aspectsEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessEthnic OriginEthnicityEtiologyFaceFactor AnalysesFactor AnalysisFoundationsGoalsGraphGuidelinesHealthHealth Care SystemsHealth and Retirement StudyHealth disparity mitigationHealth disparity reductionHeart DiseasesHeart VascularHumanHuman BiologyHypertensionImmuneImmunesIndividualInterdisciplinary ResearchInterdisciplinary StudyInterventionIntracellular Communication and SignalingInvestigatorsK01 AwardK01 MechanismK01 ProgramKnowledgeLatinx groupLatinx individualLatinx peopleLatinx populationLifeLife CycleLife Cycle StagesLife ExperienceLinkLogistic RegressionsLongitudinal StudiesLower health disparitiesMachine LearningMeasurementMeasuresMentored Research Scientist Development AwardMentored Training AwardMentorshipMetabolicMethodologyMethodsMitigate health disparitiesModern ManMorbidityMorbidity - disease rateMultidisciplinary CollaborationMultidisciplinary ResearchNational Longitudinal Study of Adolescent HealthNational Longitudinal Survey of Adolescent to Adult HealthNatureNeighborhoodsOnset of illnessOutcomePatternPhysiologicPhysiologicalPoliciesPopulationPopulation BiologyPositionPositioning AttributePredispositionPreparednessProtocolProtocols documentationPsychosocial FactorPublic HealthR-Series Research ProjectsR01 MechanismR01 ProgramRaceRacesRacial GroupReadinessReduce health disparitiesResearchResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearch Scientist Development AwardResearchersRiskRisk FactorsRoleSignal TransductionSignal Transduction SystemsSignalingSocial EnvironmentSocial SciencesSocio-economic statusSocioeconomic StatusSubgroupSusceptibilitySystemTechniquesTimeTrainingValidationVascular Hypertensive DiseaseVascular Hypertensive Disorderadolescence (12-20)adult youthadulthoodagesaging processallostatic loadapprenticeapprenticeshipbio-markersbiologicbiologic markerbiological signal transductionbiomarkercardiovascular disordercareercareer developmentcausationchronic disordercirculatory systemcohortdeep learning based neural networkdeep learning neural networkdeep neural netdeep neural networkdesigndesigningdevelopmentaldiabetesdisease causationdisease onsetdisease riskdisorder onsetdisorder riskdisparity in healthdrivingearly adulthoodearly detectionemerging adultenvironmental stressesenvironmental stressorepigeneticallyexperiencefacesfacialgradient boostinghealth disparityhealthy aginghealthy human agingheart disorderhigh blood pressurehyperpiesiahyperpiesishypertensive diseasehypertensive disorderindexinginnovateinnovationinnovativeinsightintervention programjuvenilejuvenile humanlate in lifelate lifelater in lifelater lifelife courselife spanlifespanlong-term studylongitudinal outcome studiesmachine based learningmid lifemid-lifemiddle agemiddle agedmidlifemortalitypre-clinicalpreclinicalpredictive biological markerpredictive biomarkerspredictive markerpredictive molecular biomarkerprogramsprotective factorspsychosocial variablesracialracial backgroundracial originracial populationracial subgrouprandom forestsexskillssocialsocial climatesocial contextsocial rolesocio-demographic variablessocio-economic positionsociodemographic variablessocioeconomic positionsocioenvironmentsocioenvironmentalsupervised learningsupervised machine learningtheoriestraining projectvalidationsyoung adultyoung adult ageyoung adulthood
Description preview
Chronic diseases—such as cardiovascular disease, diabetes, and Alzheimer’s Disease and Related Dementias —are leading causes of morbidity and mortality in U.S. adult, place a significant burden on the healthcare system and economy. Given that most chronic diseases are preventable, it is crucial to identify a reliable measure that can effectively…
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