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A Pragmatic Trial to Determine the Benefit of Behaviorally Enhanced Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee
Organization PHILADELPHIA VA MEDICAL CENTERLocation PHILADELPHIA, UNITED STATESPosted 1 Nov 2021Deadline 31 Oct 2025 ⚠️
VANIHUS FederalResearch GrantFY2025AccelerometerAddressAdrenal Cortex HormonesAnalgesic AgentsAnalgesic DrugsAnalgesic PreparationAnalgesicsAndroid AppAndroid ApplicationAnodynesAntinociceptive AgentsAntinociceptive DrugsAreaArthritisArthroplastyBehavioralBiologicalCartilageCartilaginous TissueCell Phone ApplicationCell phone AppCellular Phone AppCellular Phone ApplicationChronicClinic VisitsClinicalClinical TrialsClinical effectivenessCollaborationsCorticoidsCorticosteroidsCountryCross-Over DesignsCrossover DesignDataDisabling conditionDisabling health conditionDisciplineDisease ProgressionDouble-Blind MethodDouble-Blind StudyDouble-BlindedDouble-Masked MethodDouble-Masked StudyDysfunctionEffectiveness of InterventionsElementsEnsureExerciseExercise TherapyFatigueFeasibility StudiesFunctional disorderFundingGoalsHealthIncentivesInflammatory ArthritisInfrastructureInjectionsInterventionInvestigatorsJoint Prosthesis ImplantationKnee OsteoarthritisKnowledgeLack of EnergyLidocaineLignocaineMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMeasuresMediatingMedicalMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMetabolicMorbidityMorbidity - disease rateNMR ImagingNMR TomographyNuclear Magnetic Resonance ImagingObesityOrganization ChartsOutcomeOutcome AssessmentPainPainfulParticipantPatient Outcomes AssessmentsPatient ParticipationPatient Reported MeasuresPatient Reported OutcomesPatient Self-ReportPatientsPhysical FunctionPhysical activityPhysiopathologyPilot ProjectsPlayPopulationProviderQOL improvementRandomization trialRandomizedReplacement ArthroplastyReportingResearch DesignResearch PersonnelResearch ResourcesResearchersResourcesSafetySalineSaline SolutionSelf-ReportSmart Phone AppSmart Phone ApplicationSmartphone AppStudy TypeSubgroupSymptomsTechnologyTestingTherapeutic exerciseThickThicknessTimeVeteransZeugmatographyaccelerometryactivity monitoractivity trackeradiposityapp on a smartphoneapplication on a smartphonearthriticbehavior changebehavioral economicsbiologiccell phone based appcorpulencecostdesigndesigningdetermine efficacydisabilityeffective therapyeffective treatmentefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationevaluate efficacyexamine efficacyexercise treatmentexperiencefunctional improvementiOS appiOS applicationiPhone AppiPhone Applicationimprove functionimprovedimproved functional outcomesimprovements in QOLimprovements in quality of lifeinnovateinnovationinnovativejoint arthroplastyjoint replacementknee OAknee joint OAknee joint osteoarthritismobile appmobile applicationmobile device applicationmobile phone appmortalityorganizational structureosteoarthritis associated painosteoarthritis painpain killerpain medicationpain reductionpain relieverpainkillerpathophysiologyphone appphone applicationpilot studypragmatic effectiveness trialpragmatic studypragmatic trialquality of life improvementrandomisationrandomizationrandomized trialrandomized, clinical trialsrandomly assignedrecruitreduce painrehab researchrehabilitation researchresponsesatisfactionside effectsmartphone applicationsmartphone based appsmartphone based applicationsocialstudy designtreated with exercisewearablewearable devicewearable electronicswearable systemwearable technologywearable toolwearables
Applications closed.
Description preview
Knee osteoarthritis (KOA) is one of the most prevalent and disabling conditions among veterans and accounts
for high morbidity and high costs for the VA. Importantly, chronic reductions in physical activity in patients with
KOA may worsen pain, physical function, and exacerbate the metabolic consequences of obesity. The current
proposal aims to…
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