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A new animal model to elucidate mechanisms of gene regulation and embryonic patterning
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Project Summary
Hox genes serve as critical regulators of developmental processes. Disruption of their function during
embryogenesis results in dramatic “homeotic” phenotypes where regions of the body are transformed from one
identity to another. In humans, these disruptions can lead to malformation of the face, ears, limbs, and
genitalia, as well…
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