grant

A Healthy Weight Intervention for Family Stress during the Early Phases of ALL Treatment: NOURISH-ALL

Organization UNIVERSITY OF KANSAS MEDICAL CENTERLocation KANSAS CITY, UNITED STATESPosted 15 Sept 2023Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY20250-11 years oldActive Follow-upAcute Lymphoblastic LeukemiaAcute Lymphocytic LeukemiaAcute Lymphoid LeukemiaAddressAdverse ExperienceAdverse eventBehavior Conditioning TherapyBehavior ModificationBehavior TherapyBehavior TreatmentBehavioralBehavioral Conditioning TherapyBehavioral ModelBehavioral ModificationBehavioral TherapyBehavioral TreatmentCancer ControlCancer Control ScienceCancer SurvivorCancersChildChild HealthChild YouthChildhood ALLChildhood Acute Lymphoblastic LeukemiaChildhood Acute Lymphocytic LeukemiaChildhood Acute Lymphogenous LeukemiaChildhood Acute Lymphoid LeukemiaChildhood Cancer TreatmentChildhood CancersChildren (0-21)ChronicClinicalClinical TrialsCognition TherapyCognitiveCognitive PsychotherapyCognitive TherapyCognitive treatmentConditioning TherapyConduct Clinical TrialsCoping SkillsDataDevelopment PlansDevelopment and ResearchDiagnosisDietary intakeDietary qualityDisease-Free SurvivalDisparitiesDisparityDoseDrugsEatingEducationEducational aspectsEligibilityEligibility DeterminationEnrollmentEnvironmentEvent-Free SurvivalFamilyFeedbackFood IntakeFutureGlucocorticoidsGoalsHealthHealth PromotionHealth behaviorInterventionInterviewInvestigatorsKnowledgeL1 Lymphocytic LeukemiaLymphoblastic Leukemia, Acute, L1Malignant Childhood NeoplasmMalignant Childhood TumorMalignant NeoplasmsMalignant Pediatric NeoplasmMalignant Pediatric TumorMalignant TumorMalignant childhood cancerMedicationMentorshipModelingNewly DiagnosedObesityOutcomeParticipantPatientsPediatric ALLPediatric Acute Lymphoblastic LeukemiaPediatric Acute Lymphocytic LeukemiaPediatric Acute Lymphogenous LeukemiaPediatric Acute Lymphoid LeukemiaPediatric Cancer TreatmentPharmaceutical PreparationsPhasePhysical activityPlayPrecursor Cell Lymphoblastic LeukemiaPrecursor Lymphoblastic LeukemiaPreparationPreventative interventionProcessPrognosisProtocolProtocol ScreeningProtocols documentationR & DR&DResearchResearch PersonnelResearchersRoleSalutogenesisScientistSepsisShapesStressStress and CopingStructureSurvival RateSystemTargeted ResearchTestingTimeToxic effectToxicitiesTrainingTreatment ProtocolsTreatment RegimenTreatment ScheduleTreatment outcomeUnhealthy DietWeightWeight GainWeight IncreaseWorkYouthYouth 10-21acceptability and feasibilityactive followupacute lymphatic leukemiaacute lymphogenous leukemiaacute lymphomatic leukemiaadiposityarmbehavior changebehavior interventionbehavioral interventionbody weight gainbody weight increasecancer diagnosiscancer in a childcancer in childrencareercareer developmentchild with cancerchildhood malignancyclinical practicecognitive behavior interventioncognitive behavior modificationcognitive behavior therapycognitive behavioral interventioncognitive behavioral modificationcognitive behavioral therapycognitive behavioral treatmentcopingcoping strategycoping with stresscorpulencedesigndesigningdevelop therapydiet qualitydisparities in treatmentdrug/agentefficacy testingefficacy trialenrollevidence baseexcessive weight gainexperienceextreme weight gainfamily structurefamily supportfollow upfollow-upfollowed upfollowuphealth related behaviorhealthy weighthigh riskimprovedinequality in treatmentinfant ALLintervention developmentintervention for preventionintervention refinementkidslack of physical activityleukemia treatmentleukemic therapymalignancymultidisciplinaryneoplasm/cancerparticipant engagementpatient centeredpatient engagementpatient orientedpediatric cancerpediatric malignancyphysical inactivitypilot testpoor dietpreparationspreventpreventingprevention interventionpreventional intervention strategypreventive interventionpromoting healthrecruitrelapse riskresearch and developmentretention rateretention strategysedentaryserious weight gainsevere weight gainskill acquisitionskill developmentskillssocial rolestress bufferingstress managementstress-related copingstressorsurvivorshiptherapy developmenttreatment developmenttreatment disparitytreatment inequalitytreatment inequityweight gain preventionweightswt gainyoungsteryouth age
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PROJECT SUMMARY/ABSTRACT
Excessive weight gain leading to obesity is common during the early phases of pediatric acute lymphoblastic

leukemia (ALL) treatment, and results in higher risk of relapse, lower event-free survival rates, and more adverse

events during treatment. Yet, effective preventive interventions for excessive weight gain during the…

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