grant

A Balanced Reach Training Platform to Address Balance Disorders in Older and Neurologically Disabled Veterans

Organization BALTIMORE VA MEDICAL CENTERLocation BALTIMORE, UNITED STATESPosted 1 Oct 2020Deadline 31 Dec 2026
VANIHUS FederalResearch GrantFY202521+ years old65 and older65 or older65 years of age and older65 years of age or more65 years of age or older65+ years65+ years oldAccidental InjuryActivities of Daily LivingActivities of everyday lifeAddressAdultAdult HumanAffectAgeAge YearsAged 65 and OverAgingApoplexyArticular Range of MotionBalance trainingBehaviorBiomechanicsBrain TraumaBrain Vascular AccidentCareer Development AwardsCareer Development Awards and ProgramsCareer Development Programs K-SeriesCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCessation of lifeClinicClinical assessmentsControl GroupsDeathDeteriorationDevelopmentDiabetes MellitusDiagnosisDiagnosticDisabled PersonsDisabled PopulationDiseaseDisorderElderlyElementsEngineeringEquilibriumFunctional impairmentGeneral PopulationGeneral PublicGoalsHandicappedHealth Care SystemsHigh PrevalenceHourHumanImpairmentIndividualInjuryInterventionJoint Range of MotionK-AwardsK-Series Research Career ProgramsLifeLower ExtremityLower LimbMeasuresMembrum inferiusMethodsModern ManMorbidityMorbidity - disease rateMovementMusculoskeletalNervous System DiseasesNervous System DisorderNeurologicNeurologic DisordersNeurologicalNeurological DisordersObesityPNS DiseasesPatientsPeople with DisabilitiesPerceptionPerformancePeripheral Nerve DiseasesPeripheral Nervous System DiseasesPeripheral Nervous System DisordersPeripheral NeuropathyPersonsPersons with DisabilitiesPopulationPosturePrevalenceProtocolProtocols documentationPsychophysicsQOCQuality of CareResearchResearch Career ProgramResistanceRiskStrokeStructureSystemTestingTherapeutic InterventionTimeTrainingTraining ActivityTraumatic Brain InjuryTreatment CostTreatment ProtocolsTreatment RegimenTreatment ScheduleUnintentional InjuryVestibular DiseasesVestibular disorderVestibular system disorderVestibulopathyVeteransWalkingabove age 65accurate diagnosisadiposityadulthoodadvanced ageafter age 65age 65 and greaterage 65 and olderage 65 or olderageage of 65 years onwardaged 65 and greateraged 65+aged ≥65agesbalancebalance disorderbalance functionbalance impairmentbasebasesbiomechanicalbody movementbrain attackcare costscareer developmentcerebral vascular accidentcerebrovascular accidentclinical efficacyclinical trainingcombatcorpulencecostdaily living functiondaily living functionalitydecline in functiondecline in functional statusdesigndesigningdevelopmentaldiabetesdisabilitydisableddisabled individualdisabled peopledisturbed balancedosageequilibration disorderequilibrium disorderexercise trainingfall injuryfall related injuryfall riskfallsfunctional abilityfunctional capacityfunctional declinefunctional status declinegeriatrichuman old age (65+)improvedindividuals with disabilitiesinjuriesinjurious fallsinnovateinnovationinnovativeinstrumentintervention therapylocomotor learningmilitary veteranmotor learningmuscle degenerationneurological diseaseneurophysiologicalneurophysiologynew diagnosticsnext generation diagnosticsnovelnovel diagnosticsolder adultolder adulthoodover 65 yearsportabilitypsychophysicalrange of motionrehab researchrehabilitation researchresistantresponsesarcopeniasarcopenicsenior citizenstrokedstrokessuccesstooltrain balancetraining moduletraumatic brain damagetrendveteran population≥65 years
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Full Description

Falls are by far the leading cause of accidental injury and death in older adults. The Veteran population is
more severely affected by falls since it is significantly older than the overall population (45% over 65 years of

age vs. 13%); and Veterans would benefit substantially more from an accurate diagnosis and treatment of fall

propensity. Despite its importance, much is still unknown about the manner in which balance control is

compromised by age and disease. Therapeutic interventions for people who are at risk of falling have proven

to be of limited utility. Engineering methods are well suited to study and evaluate balance; but have to date

been applied to overly simplified scenarios that lack the complexity to probe the musculoskeletal and

neurophysiological bases for balance and falls.

The long term objective of this research, which began with a VA Rehabilitation Research & Development

(RR&D) Career Development Award (CDA-2), is to develop improved directives and protocols for the diagnosis

and treatment of balance-related posture and movement coordination problems. This proposal significantly

advances engineering methods to address existing gaps in the diagnosis and treatment of balance

impairments through the development of a Balanced Reach Training Protocol (BRTP). The BRTP

continuously challenges subjects to perform reaching tasks at the limits of their balance for an extended

period of time, and increases these limits as subjects demonstrate improved performance. The goal of this

tool is to quantitatively assess and improve at-risk individuals' ability to maintain balance when disturbed by

volitional movements of the body and its parts—an important class of balance disturbances integral to many

activities of daily living that can precipitate falls. The BRTP focuses on performance at and just beyond the

limits of balance, unlike most such tests and training protocols that do not challenge subjects in this way. The

BRTP's most immediate and salient metric is the limiting boundary of standing reach; and we hypothesize

that expanding this boundary, as the BRTP is designed to do, will improve balance and make individuals more

resistant to falls (in the context of expected balance disturbances).

Confirmation of this hypothesis could provide a new perspective on existing training protocols' modest

success rates, and direction for the design of new protocols with the potential to significantly improve these

rates. [Though the BRTP is a training platform, we also believe that the performance metrics and analytical

results produced by it can form the basis for new diagnostic measures that more reliably and precisely

quantify and explain balance performance problems; and track changes in them over time.] Such

diagnostic and treatment protocols would be particularly beneficial to the VA Health Care System, as it

would lead to improvements in: patient throughput, quality of care, and treatment costs. Though this

proposal targets the aging Veteran population, the BRTP is a general tool that can aid in the diagnosis and

treatment of balance disorders arising from conditions other than aging. These include obesity, diabetes

(which often leads to lower extremity muscle degeneration and peripheral neuropathy), sarcopenia,

vestibular disorders, and neurological disorders such as stroke. Veterans whose balance has been

compromised by Traumatic Brain Injury (TBI) (whether combat-related or not) may also benefit from the BRTP.

Grant Number: 5I01RX003096-05
NIH Institute/Center: VA

Principal Investigator: Joseph Barton

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