2026 Lymphatics Gordon Research Conference and Seminar

PROJECT SUMMARY
The objectives of the 2026 GRC “Lymphatics” are to present state-of-the-art research on the lymphatic vascular
system, to fuel scientific exchange across scientific disciplines and expertise, and to spearhead new ideas and
collaborations. The meeting will bring together investigators from all backgrounds and from all career stages,
converging on lymphatics as one common theme. Specific Aims are (1) To present conceptual advances in
research of the lymphatic vascular system and its pathologies; (2) To discuss paradigm shifting findings of
lymphatics in different organ systems and their contribution to disease; (3) To integrate knowledge from different
disciplines; and (4) To nurture junior investigators and trainees entering the lymphatic research field. Sessions
will cover conceptual advances in development and disease of lymphatic vessels from basic aspects to potential
clinical applications. The meeting will highlight recent insights into the diversity and organ-specificity of lymphatic
endothelium. Novel molecular regulators for lymphatic vasculature during bone development, Schlemm’s canal
in the eye and lacteals in the intestine will be discussed. New factors regulating lymphangiogenesis and
lymphatic integrity will be introduced. Advances in research on lymphatic malformations, lymphedema and other
congenital lymphatic diseases will be discussed. The meeting will also present emerging concepts on the role
of lymphatics in atherosclerosis, myocardial infarction, and congestive heart failure. Paradigm shifts in the field
will be presented, and crosstalk between lymphatics and immune system discussed. Advances in understanding
how lymphatics contribute to disease, including cardiovascular inflammation, cancer, autoimmune and
neurodegenerative diseases will be highlighted. A key goal for this meeting is to serve as a platform for growth
of lymphatic research, and for helping to promote new scientists entering this research field. Abundant
opportunities for the presentation of research by early career investigators will be provided. The GRS on
Lymphatics organized by junior investigators will provide opportunities exclusively for junior investigators to
present their work and form collaborations. Aside from presentation and poster sessions, a career development
session will also be held during GRS to provide guidance to those just getting their start in the lymphatic research
field, and to discuss strategies for how to navigate issues impeding lymphatic research or obstacles to
participation by incoming lymphatic researchers. A patient session will also be held to allow researchers to hear
from those suffering from lymphatic diseases and hear their perspective on the potential promise of translating
lymphatic research into new therapies. The sponsoring organization is dedicated to advancing the frontiers of
science. In accordance with its mission, this conference will place emphasis on the presentation of unpublished
data, high-quality science and rich discussions in many fields, such as cardiovascular disease, cancer,
immunology, metabolism and neurobiology. We anticipate that the opportunities provided to young investigators
participating in this conference will facilitate their rise as future leaders of the lymphatic research field.

Grant Number: 1R13HL184878-01
NIH Institute/Center: NIH
Principal Investigator: Hong Chen