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1Florida Alzheimer's Disease Research Center Clinical Core
Organization UNIVERSITY OF FLORIDALocation GAINESVILLE, UNITED STATESPosted 15 Jun 2020Deadline 30 Apr 2026 ⚠️
NIHUS FederalResearch GrantFY2025A β-42A β42A-beta 42A-beta42AD dementiaAD related dementiaADRDAPOEAbeta-42Abeta42AcculturationActive Follow-upAffectAfrican AmericanAfro AmericanAfroamericanAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimer's and related dementiasAlzheimer's dementia and related dementiaAlzheimer's dementia or related dementiaAlzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementiaAlzheimer's disease related dementiaAlzheimers DementiaAmentiaAmyloidAmyloid SubstanceAmyloid beta-42Amyloid beta42Amyloid β-42Amyloid β42Amyloidβ-42Amyloidβ42Apo-EApoE proteinApolipoprotein EArteriosclerotic DementiaAutopsyAβ-42Aβ42Biological MarkersBlood VesselsBrainBrain Nervous SystemBrain PathologyBrain VascularBrain regionClassificationClinicalClinical TrialsCognitionCognitiveCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive function abnormalCollaborationsCommunitiesComplementComplement ProteinsConsentCultural AssimilationDataDecrease disparityDementiaDiagnosisDiagnosticDiseaseDisorderDisturbance in cognitionEarly DiagnosisEducationEducational aspectsElderlyElementsEncephalonEnrollmentEnsureEpidemiologyEvaluationFloridaFundingGeneticGenotypeGoalsHispanicHispanic PopulationsHispanic groupHispanic individualHispanic peopleHispanicsImageImpaired cognitionIndividualIndividuals from minorityIndividuals of minorityInvestigationInvestigatorsLB diseaseLB disorderLanguageLewy Body DiseaseLewy body disorderLewy diseaseLewy disorderLongitudinal StudiesLower disparityMR ImagingMR TomographyMRIMRI ScansMRIsMT-bound tauMagnetic Resonance ImagingMagnetic Resonance Imaging ScanMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMedical centerMethodologyMethodsMinority GroupsMinority PeopleMinority PopulationMinority individualMonitorNIAAANMR ImagingNMR TomographyNational Institute on Alcohol Abuse and AlcoholismNerve DegenerationNeuron DegenerationNeuropsychologic TestsNeuropsychological TestsNeuropsychologiesNeuropsychologyNon-HispanicNonhispanicNot Hispanic or LatinoNuclear Magnetic Resonance ImagingPETPET ScanPET imagingPETSCANPETTParalysis AgitansParkinsonParkinson DiseaseParkinsonianParkinsonian ConditionParkinsonian DiseasesParkinsonian DisordersParkinsonian SyndromeParkinsonismParticipantPathologyPerformancePhenotypePositron Emission Tomography Medical ImagingPositron Emission Tomography ScanPositron-Emission TomographyPrimary ParkinsonismPrimary Senile Degenerative DementiaProtocolProtocols documentationQualifyingR-Series Research ProjectsR01 MechanismR01 ProgramRad.-PETResearchResearch ActivityResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearchersSiteSpanish/EnglishStandardizationSystematicsTrainingUnderrepresented Ethnic MinorityUnderrepresented MinorityUniversitiesVascular DementiaVascular DiseasesVascular DisorderZeugmatographyactive followupadvanced agebilingualbilingualismbio-markersbiologic markerbiomarkerblood vessel disorderblood-based biomarkerblood-based markercerebral vascularcerebro-vascularcerebrovascularcerebrovascular contributions to dementiaclinical centerclinical research siteclinical siteco-morbidco-morbiditycognitive changecognitive dysfunctioncognitive losscohortcomorbiditycomplementationdisparity reductionearly detectionenrollepidemiologicepidemiologicalethnic diversityethnically diversefollow upfollow-upfollowed upfollowupgeriatricimagingimprovedinstrumentlong-term studylongitudinal outcome studiesmicrotubule bound taumicrotubule-bound taumild cognitive disordermild cognitive impairmentmitigate disparitynecropsyneural degenerationneural imagingneuro-imagingneurodegenerationneurodegenerativeneuroimagingneurological degenerationneurological imagingneuronal degenerationneuropathologicneuropathologicalneuropathologyneuropsychologicnovelolder adultolder adulthoodpositron emission tomographic (PET) imagingpositron emission tomographic imagingpositron emitting tomographypostmortempre-clinical studypreclinical studyprimary degenerative dementiaracial diversityracially diverserecruitreduce disparityreduction in disparityresearch studyretention rateretention strategysenile dementia of the Alzheimer typesenior citizensuccesstautau Proteinstau factorunder-representation of minoritiesunder-represented minorityunderrepresentation of minoritiesvascularvascular contributions in dementiavascular contributions to dementiavascular dysfunctionvascular related dementiavasculopathyτ Proteins
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Description preview
The goal of the 1Florida ADRC is to advance the understanding of Alzheimer’s disease and Related Disorders
(ADRDs), especially in underrepresented minority groups. Among 370 participants currently recruited at Mount
Sinai Medical Center (MSMC), 60% are Hispanic, with a retention rate of ~80%, over 50% are normal or have
various stages of Mild…
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