grant
Virus-Host Interactions: Induction and Evasion of Host Innate Immunity
Organization NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESLocation UNITED STATES
NIHUS FederalResearch GrantFY2025(IFN) α(IFN)-α(IFN)αATRAActive OxygenAffectAlferonAmino AcidsAnimal ModelAnimal Models and Related StudiesAnti-viral ResponseAntigen PresentationAreaAutomobile DrivingB-Cell ActivationBasal Transcription FactorBasal transcription factor genesBiologyBreakbone Fever VirusCD4 CellsCD4 Positive T LymphocytesCD4 T cellsCD4 helper T cellCD4 lymphocyteCD4+ T-LymphocyteCD4-Positive LymphocytesCNS infectionCapsidCategoriesCell BodyCell Communication and SignalingCell FunctionCell PhysiologyCell ProcessCell SignalingCell SurvivalCell ViabilityCell-Mediated Lympholytic CellsCellsCellular FunctionCellular PhysiologyCellular ProcessCentral Nervous System InfectionsCentral Nervous System Infectious DiseaseCentral Nervous System Infectious DisorderCerebrumCharacteristicsChemotactic CytokinesClinicalClosure by LigationComplexCoronaviridaeCoronavirusCulicidaeCytolytic T-CellCytotoxic T CellCytotoxic T-LymphocytesDENVDendritic CellsDengue VirusDengue fever virusDevelopmentEC 2.1.1EC 2.7.7.48Egypt 101 virusElectron TransportEndoplasmic ReticulumErgastoplasmEsteroproteasesEventFlavivirusFlavivirus InfectionsGene ExpressionGene TranscriptionGeneral Transcription Factor GeneGeneral Transcription FactorsGeneralized GrowthGenesGeneticGenetic TranscriptionGenomeGoalsGroup B ArbovirusGrowthHomologous Chemotactic CytokinesHost resistanceHourHumanHyperactivityIFNIFN AlphaIFN αIFN-αIFNaIFNαImmuneImmune Cell ActivationImmune EvasionImmune responseImmune systemImmunesImmunityInfectionInflammation MediatorsInflammatory ResponseInnate Immune ResponseInnate ImmunityIntercrinesInterferon Alfa-n3Interferon Type IInterferon-αInterferonsIntracellular Communication and SignalingIxodidaJAK kinaseJanus kinaseJapanese B Encephalitis VirusJapanese encephalitis virusLaboratoriesLeukocyte InterferonLigationLymphoblast InterferonLymphoblastoid InterferonM mulattaM. mulattaMacaca mulattaMacaca rhesusMacrophageMembraneMetabolicMethyltransferaseMitochondriaModelingModern ManMosquitoesMφNIAIDNational Institute of Allergy and Infectious DiseaseNative ImmunityNatural ImmunityNon-Polyadenylated RNANon-Specific ImmunityNon-structural ProteinNonspecific ImmunityNonstructural ProteinNuclearNucleic AcidsORFsOpen Reading FramesOrganoidsOrthocoronavirinaeOrthoflavivirusOxygen RadicalsPathway interactionsPattern recognition receptorPeptidasesPeptide HydrolasesPersonsPolyproteinsPro-OxidantsProtease GeneProteasesProtein Coding RegionProteinasesProteinsProteolytic EnzymesRBCC/TRIM MotifRNARNA ExpressionRNA Gene ProductsRNA ProcessingRNA ReplicaseRNA VirusesRNA-Dependent RNA PolymeraseRNA-Directed RNA PolymeraseReactive Oxygen SpeciesReceptor ProteinReceptor SignalingResearchResistanceRespirationRetinoic AcidRetroviridaeRetrovirusesRhesus MacaqueRhesus MonkeyRibonucleic AcidRoleSIS cytokinesSignal PathwaySignal TransductionSignal Transduction PathwaySignal Transduction SystemsSignalingSiteSubcellular ProcessT-Cell Antigen Receptor-Interacting MoleculeT-Cell Receptor-Associated Transmembrane Adaptor 1T-CellsT-LymphocyteT4 CellsT4 LymphocytesTLR proteinTRAT1TRC-Interacting MoleculeTRIMTRIM GeneTRIM MotifTherapeuticTick-Borne EncephalitisTick-Borne Encephalitis VirusTick-borne Viral EncephalitisTickborne Encephalitis VirusTicksTissue GrowthToll-Like Receptor Family GeneToll-like receptorsTrans Vitamin A AcidTranscriptionTranscription ActivationTranscription Factor Proto-OncogeneTranscription factor genesTranscriptional ActivationTransducersTranslatingTransmissionTretinoinTretinoinumTripartite MotifVaccineeVaccinesVeiled CellsViralViral DiseasesViral Hemorrhagic FeversViral PathogenesisViremiaVirusVirus DiseasesVirus ReplicationVirus-RetrovirusVitamin A AcidWNVWest Nile virusWorkYellow FeverYellow Fever VaccineYellow fever virusZIKVZika Virusactivated B cellsadaptive immune responseall-trans-Retinoic Acidall-trans-Vitamin A acidaminoacidarthropod transmissionarthropod transmittedarthropod-bornearthropodbornebiological signal transductionburden of diseaseburden of illnesscerebralchemoattractant cytokinechemokinecorona viruscytokinedevelopmentaldisease burdendrivingelectron transferhemorrhagic feverhost responsehuman pathogenimmune activationimmune evasiveimmune system responseimmunoresponseimprovedinflammatory mediatorinnate immune mechanismskiller T cellmembermembrane structuremethylasemitochondrialmodel of animalmosquito-bornemosquitobornemouse modelmurine modelneutralizing antibodynovelontogenypathogenpathogenic viruspathwaypreventpreventingprogramsreceptorresistantrespiratory mechanismresponsesocial rolesuccessthymus derived lymphocytetrans-Retinoic Acidtranscription factortransmethylasetransmission processvaccinated individualvaccinated participantvaccinated patientvaccinated personvaccinated subjectvaccine against yellow fevervaccine effectivenessviraemiaviral infectionviral multiplicationviral pathogenviral replicationviral sepsisvirus host interactionvirus infectionvirus multiplicationvirus pathogenvirus pathogenesisvirus-induced diseasevirusemiayellow fever virus vaccinezikav
Description preview
The host innate immune response is triggered within hours of virus infection. As a whole, its function is to limit virus replication at local sites of infection and to orchestrate development of the adaptive immune response. Viruses are typically recognized by cellular pattern recognition receptors (PRRs), including toll-like receptors (TLRs) and…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click