grant
Virology and Immunology Technology Core
Organization NORTHWESTERN UNIVERSITYLocation CHICAGO, UNITED STATESPosted 9 Apr 2015Deadline 31 Jul 2030
NIHUS FederalResearch GrantFY2025AIDSAIDS VirusAcquired Immune DeficiencyAcquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome VirusAddressAffinity ChromatographyAirAnimal ModelAnimal Models and Related StudiesAnimalsAssayAutopsyAwardBindingBioassayBiologic ModelsBiologicalBiological AssayBiological MarkersBiological ModelsBiology of AgingBlood PlasmaBody TissuesCRISPR approachCRISPR based approachCRISPR editing screenCRISPR methodCRISPR methodologyCRISPR screenCRISPR techniqueCRISPR technologyCRISPR toolsCRISPR-CAS-9CRISPR-based methodCRISPR-based screenCRISPR-based techniqueCRISPR-based technologyCRISPR-based toolCRISPR/CAS approachCRISPR/Cas methodCRISPR/Cas technologyCRISPR/Cas9CRISPR/Cas9 screenCRISPR/Cas9 technologyCUT&RUNCareer CounselingCareer GuidanceCas nuclease technologyCell BodyCell IsolationCell LineCell SegregationCell SeparationCell Separation TechnologyCellLineCellsCellular AssayChIP SequencingChIP-seqChIPseqChicagoCleavage Targets and Release Using NucleaseCleavage Under Targets and Release Using NucleaseClinicalClustered Regularly Interspaced Short Palindromic Repeats approachClustered Regularly Interspaced Short Palindromic Repeats methodClustered Regularly Interspaced Short Palindromic Repeats methodologyClustered Regularly Interspaced Short Palindromic Repeats techniqueClustered Regularly Interspaced Short Palindromic Repeats technologyCollaborationsCommunitiesComplementary DNAConsultationsDNADNA deliveryDataDeoxyribonucleic AcidDevelopmentElectron MicroscopyEpitheliumExperimental DesignsExperimental ModelsFacultyFlow CytofluorometriesFlow CytofluorometryFlow CytometryFlow MicrofluorimetryFlow MicrofluorometryFutureGene ActivationGene TranscriptionGenesGenetic TranscriptionGenomeGenomicsHIVHumanHuman Immunodeficiency VirusesHypoxiaHypoxicIllinoisImageImmunologyInfectionInflammationInfrastructureInterest GroupInterventionInvestigatorsJournalsKnock-inLAV-HTLV-IIILaboratoriesLeadershipLightLiquid substanceLymphadenopathy-Associated VirusMacacaMacaqueMacrophageMagazineMass Photometry/Spectrum AnalysisMass SpectrometryMass SpectroscopyMass SpectrumMass Spectrum AnalysesMass Spectrum AnalysisMentorsMicroscopyMissionModel SystemModern ManModificationMolecular InteractionMolecular VirologyMφNHP modelsNational Institutes of HealthNeuropathogenesisNon-Polyadenylated RNANucleic AcidsOccupational GuidanceOrganoidsOxygen DeficiencyPET/CTPET/CT scanPersonsPhotoradiationPhylogenetic AnalysisPhylogeneticsPlasmaPlasma SerumPoly APoly(rA)Post-Translational Modification Protein/Amino Acid BiochemistryPost-Translational ModificationsPost-Translational Protein ModificationPost-Translational Protein ProcessingPosttranslational ModificationsPosttranslational Protein ProcessingPreparationPreventionProductionProtein GlycosylationProtein ModificationProteinsProteomicsProvirusesRNARNA ExpressionRNA Gene ProductsRectumResearchResearch PersonnelResearch ResourcesResearch SpecimenResearchersResourcesRestReticuloendothelial System, Serum, PlasmaRibonucleic AcidRoleSIVServicesSimian Immunodeficiency VirusesSpecimenStagingStrains Cell LinesStrategic PlanningStudy modelsSwabSystemSystems BiologyT-CellsT-LymphocyteTechniquesTechnologyTissuesTrainingTranscriptionUnited States National Institutes of HealthUniversitiesUpdateViralVirionVirusVirus ParticleVirus-HIVVocational CounselingVocational Guidanceaffinity purificationaging delayattenuate agingbio-markersbiologicbiologic markerbiomarkercDNAcareer counselorcell assaycell sortingchromatin immunoprecipitation coupled with sequencingchromatin immunoprecipitation followed by sequencingchromatin immunoprecipitation with sequencingchromatin immunoprecipitation-seqchromatin immunoprecipitation-sequencingclustered regularly interspaced short palindromic repeats screenco-morbidco-morbiditycomorbidityconsultationcultured cell linedecelerate agingdeep sequencingdelay age relateddeliver DNAdevelopmentaldiagnostic approachdiagnostic strategyentire genomeepigenomicsexecutive coachingexperienceflow cytophotometryfluidfull genomefunctional genomicsgenetic linkagehiPSChuman iPShuman iPSChuman induced pluripotent cellhuman induced pluripotent stem cellshuman inducible pluripotent stem cellshuman inducible stem cellshuman tissuehumanized micehumanized mouseimagingimprovedin vivoinduced human pluripotent stem cellsinsightknockinknockout genelife spanlifespanliquidmetabolism measurementmetabolomicsmetabonomicsmicrobiomemodel of animalmodel-based simulationmodels and simulationmultiomicsmultiple omicsmultiplex assaynanopore based sequencingnanopore long read seqnanopore long-read sequencingnanopore seqnanopore sequencingnanopore-based long-read sequencingnecropsynon-human primatenonhuman primatenonhuman primate modelspanomicspause agingpolyadenylatepositron emission computed tomographypostmortempostpone age relatedpreparationsprotein purificationprotein structureprotein structuresproteins structurereconstructionretards agingscreeningscreeningsslow agingslow down agingslow the rate of agingsocial rolespatial RNA sequencingspatial gene expression analysisspatial gene expression profilingspatial resolved transcriptome sequencingspatial transcriptome analysisspatial transcriptome profilingspatial transcriptome sequencingspatial transcriptomicsspatially resolved transcriptomicsspatio transcriptomicssynergismthymus derived lymphocytetranscriptomicsvectorvirologyvirus host interactionwhole genomework groupworking group
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Modified Project Summary/Abstract Section
The Virology and Immunology Technology Core (VITC) has a mission, which is congruent with Overall Aim 1, to support the HIV research community across Chicago in rigorously characterizing biological mechanisms, enabling discovery of still-needed interventions and diagnostic approaches that improve…
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