grant
Using DNA Repair and Damage as a Tool in Personalizing Aging and Aging Related Diseases
Organization RLR VA MEDICAL CENTERLocation INDIANAPOLIS, UNITED STATESPosted 1 Apr 2025Deadline 31 Mar 2030
VANIHUS FederalResearch GrantFY202521+ years oldAccelerationActive Follow-upAdultAdult HumanAdvanced CancerAdvanced Malignant NeoplasmAffectAgeAgingAssayBioassayBiologicalBiological AgingBiological AssayBlackBlack raceBlood SampleBlood specimenBreastCOPDCancer PatientCancersCell BodyCellsCellular injuryCharacteristicsChronic Obstruction Pulmonary DiseaseChronic Obstructive Lung DiseaseChronic Obstructive Pulmonary DiseaseChronologyClinical TrialsCorrelation StudiesCoupledCryofixationCryopreservationDNA AlterationDNA DamageDNA Damage RepairDNA Double Strand BreakDNA InjuryDNA RepairDNA Repair GeneDNA Repair PathwayDNA Sequence AlterationDNA copy numberDNA damage during agingDNA damage in agingDNA damage with ageDNA damage with agingDNA lesionDNA repair proteinDataDevelopmentDiagnosisDiet ModificationDietary InterventionDietary ModificationsDiseaseDisorderDoctor of PhilosophyEffectivenessElderlyEnrollmentEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessEpithelial CellsExerciseFlow CytofluorometriesFlow CytofluorometryFlow CytometryFlow MicrofluorimetryFlow MicrofluorometryGenderGeneticGenetic AlterationGenome InstabilityGenomic InstabilityGoalsHospital AdmissionHospitalizationHumanHypertensionIRBIRBsIndividualInflammatoryInstitutional Review BoardsInterventionLengthLife Style ModificationLinkLiteratureLung DiseasesMalignant NeoplasmsMalignant TumorMalignant Tumor of the LungMalignant neoplasm of lungMeasuresMitochondrial DNAModern ManMononuclearNHEJNasal EpitheliumNon-HispanicNon-Homologous End JoiningNon-homologous DNA End JoiningNonhispanicNonhomologous DNA End JoiningNonhomologous End JoiningNot Hispanic or LatinoNucleotide Excision RepairNutrition InterventionsNutritional InterventionsOutcomeOutcome StudyPBMCPathway interactionsPatternPeripheralPeripheral Blood Mononuclear CellPersonsPh.D.PhDPhysical FitnessPhysiologicPhysiologicalPopulationProcessPulmonary CancerPulmonary DiseasesPulmonary DisorderPulmonary malignant NeoplasmResearchRiskRisk FactorsRisk ReductionRoleSequence AlterationStatistical CorrelationTimeUnscheduled DNA SynthesisVascular Hypertensive DiseaseVascular Hypertensive DisorderVeteransWorkaccelerated agingaccelerated biological ageaccelerated biological agingactive followupadulthoodadvanced ageage accelerationage associatedage associated DNA damageage correlatedage dependentage linkedage relatedage related DNA damageage specificagedagesaging associated DNA damageaging associated diseaseaging associated disordersaging biological markeraging biomarkeraging markeraging processaging related DNA damageaging related diseaseaging related disordersbiologicbiological agebiological process of agecell damagecell injurycellular damagechronic obstructive pulmonary disordercigarette smokingcigarette usecold preservationcold storagecytokinedamage to cellsdevelopmentaldiet alterationdiet and exercisediet interventiondietary alterationdisease associated with agingdisease of agingdisease of the lungdisorder of agingdisorder of the lungdisorders associated with agingdisorders related to agingenrollepigenetic biomarkerepigenetic markerepigenetic regulationepigeneticallyflow cytophotometryfollow upfollow-upfollowed upfollowupgenome wide methylationgenomewide methylationgenomic alterationgenomic biomarkergenomic markergeriatricglobal methylationhallmarks of aginghealthy volunteerhigh blood pressurehigh risk grouphigh risk individualhigh risk peoplehigh risk populationhyperpiesiahyperpiesishypertensive diseasehypertensive disorderimprovedindividualized biomarkersinjury to cellslife style interventionlifestyle interventionlifestyle modificationlung cancerlung developmentlung disordermalignancyminimally invasivemodifiable lifestyle factorsmtDNAneoplasm/canceroutcome predictionpathwaypersonalized biomarkerspillars of agingpredictive biological markerpredictive biomarkerspredictive markerpredictive molecular biomarkerprematureprematurityreduce riskreduce risksreduce that riskreduce the riskreduce these risksreduces riskreduces the riskreducing riskreducing the riskrepairrepairedrisk-reducingscreeningscreeningssenior citizensocial rolestudy populationtargeted drug therapytargeted drug treatmentstargeted therapeutictargeted therapeutic agentstargeted therapytargeted treatmenttelomeretherapeutic targettool
Description preview
This project aims to use DNA repair and damage as a tool to personalize aging and aging-related diseases,
with a particular focus on US veterans who are at increased risk for lung diseases such as COPD and lung
cancer. The global population, including our veterans, is aging rapidly, with the percentage of people aged 60
and over projected to equal…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click