grant

Understanding protection against norovirus at the maternal-child interface

Organization UNIV OF NORTH CAROLINA CHAPEL HILLLocation CHAPEL HILL, UNITED STATESPosted 6 Dec 2018Deadline 31 Jan 2029
NIHUS FederalResearch GrantFY20260-11 years oldAccountingAntibodiesAssayBacteriaBioassayBiological AssayBirthBlood Group AntigensBlood SerumBreast FeedingBreast MilkBreastfed infantBreastmilkCells Placenta-TissueCharacteristicsChildChild YouthChildhoodChildren (0-21)ClinicalClinical InvestigatorClinical ResearchClinical StudyCohort StudiesCommunicable DiseasesComplementComplement ProteinsComplexDataDevelopmentEpidemiologyEpithelial CellsFamily PracticeFecesFundingFutureGI microbiomeGI microbiotaGastroenteritisGastrointestinal microbiotaGenotypeGlycobiologyGoalsHPLCHealth InstructionHealth TutoringHealth educationHigh Performance Liquid ChromatographyHigh Pressure Liquid ChromatographyHigh Speed Liquid ChromatographyHumanHuman MilkHuman Mother's MilkImmuneImmunesImmunityIndividualInfantInfectionInfectious DiseasesInfectious DisorderInterventionInvestigatorsK24 AwardLaboratoriesLactationLeadershipLearningLifeLow-resource areaLow-resource communityLow-resource environmentLow-resource regionLow-resource settingMammary Gland MilkMaternal antibodyMeasuresMentorsMentorshipMethodsMid-Career Clinical Scientist Award (K24)Modern ManMother's MilkMothersNational Institutes of HealthNatural HistoryNicaraguanNormal PlacentomaNorovirusNorth CarolinaNorwalk-like VirusesOligosaccharidesOwnershipParturitionPerformancePhysiciansPlacentaPlacenta Embryonic TissuePlacentomePlayPredisposing FactorPredispositionPreventionR-Series Research ProjectsR01 MechanismR01 ProgramReceptor ProteinResearchResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearch ResourcesResearchersResource-constrained areaResource-constrained communityResource-constrained environmentResource-constrained regionResource-constrained settingResource-limited areaResource-limited communityResource-limited environmentResource-limited regionResource-limited settingResource-poor areaResource-poor communityResource-poor environmentResource-poor regionResource-poor settingResourcesRiskRisk FactorsRoleRotavirus VaccinesSamplingSapovirusSapporo-like VirusesScientistSerumShapesSusceptibilityTimeTraining ProgramsUnited States National Institutes of HealthUniversitiesViral GastroenteritisWeaningWomanWorkbiobankbiorepositorybreastfeeding infantburden of diseaseburden of illnesscareercareer developmentcohortcohort research studycohort surveycomplementationdevelop a vaccinedevelop vaccinesdevelopment of a vaccinedevelopmentaldigestive tract microbiomedisease burdenearly childhoodenteral infectionenteric infectionenteric microbial communityenteric microbiomeenteric microbiotaenteric pathogen infectionenteropathogen infectionenteropathogenic infectionepidemiologicepidemiologicalfamily medicinegastrointestinal microbial floragastrointestinal microbiomeglobal healthgut communitygut floragut microbe communitygut microbial communitygut microbial compositiongut microbial consortiagut microbiomegut microbiome of infantgut microbiotagut microbioticgut microfloragut-associated microbiomehuman milk oligosaccharidesinfant gut microbiomeinfected with enteropathogeninterdisciplinary approachintestinal biomeintestinal epitheliumintestinal floraintestinal infectionintestinal microbiomeintestinal microbiotaintestinal microfloraintestinal tract microfloraintestine infectionkidslactatinglactationalmaternal milkmaternal serummicrobiome community compositionmicrobiome compositionmicrobiome species compositionmicrobiome structuremultidisciplinary approachneonate gut microbiomenewborn gut microbiomenext generationpathogenpatient oriented researchpatient oriented studypediatricpreventpreventingreceptorskill acquisitionskill developmentskillssocial rolestoolvaccine developmentyoungster
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Description preview

MODIFIED ABSTRACT SECTION
This K24 renewal builds upon the successful clinical research and mentorship performed by the candidate,

Sylvia Becker-Dreps, MD, MPH. As a natural extension of Dr. Becker-Dreps’ previous work on human norovirus

(NoV), this proposal expands her research skillset to investigate maternal protection against NoV in early…

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Understanding protection against norovirus at the maternal-child interface — UNIV OF NORTH CAROLINA CHAPEL HILL | UNITED | Dev Procure