grant
Understanding protection against norovirus at the maternal-child interface
Organization UNIV OF NORTH CAROLINA CHAPEL HILLLocation CHAPEL HILL, UNITED STATESPosted 6 Dec 2018Deadline 31 Jan 2029
NIHUS FederalResearch GrantFY20250-11 years oldAccountingAntibodiesAssayBacteriaBioassayBiological AssayBirthBlood Group AntigensBlood SerumBreast FeedingBreast MilkBreast fedBreast fed infantBreastfedBreastfed infantBreastfeedingBreastmilkCells Placenta-TissueCharacteristicsChildChild YouthChildhoodChildren (0-21)ClinicalClinical InvestigatorClinical ResearchClinical StudyCohort StudiesCommunicable DiseasesComplementComplement ProteinsComplexConcurrent StudiesDataDevelopmentEpidemiologyEpithelial CellsFamily PracticeFecesFundingFutureGI microbiomeGI microbiotaGastroenteritisGastrointestinal microbiotaGenotypeGlycobiologyGoalsHPLCHealth InstructionHealth TutoringHealth educationHigh Performance Liquid ChromatographyHigh Pressure Liquid ChromatographyHigh Speed Liquid ChromatographyHumanHuman MilkHuman Mother's MilkImmuneImmunesImmunityIndividualInfantInfectionInfectious DiseasesInfectious DisorderInterventionInvestigatorsK24 AwardLaboratoriesLactationLeadershipLearningLifeLow-resource areaLow-resource communityLow-resource environmentLow-resource regionLow-resource settingMammary Gland MilkMaternal antibodyMeasuresMentorsMentorshipMethodsMid-Career Clinical Scientist Award (K24)Modern ManMother's MilkMothersNational Institutes of HealthNatural HistoryNicaraguanNormal PlacentomaNorovirusNorth CarolinaNorwalk-like VirusesOligosaccharidesOwnershipParturitionPerformancePhysiciansPlacentaPlacenta Embryonic TissuePlacentomePlayPredisposing FactorPredispositionPreventionR-Series Research ProjectsR01 MechanismR01 ProgramReceptor ProteinResearchResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearch ResourcesResearchersResource-constrained areaResource-constrained communityResource-constrained environmentResource-constrained regionResource-constrained settingResource-limited areaResource-limited communityResource-limited environmentResource-limited regionResource-limited settingResource-poor areaResource-poor communityResource-poor environmentResource-poor regionResource-poor settingResourcesRiskRisk FactorsRoleRotavirus VaccinesSamplingSapovirusSapporo-like VirusesScienceScientistSerumShapesSusceptibilityTimeTraining ProgramsUnderrepresented GroupsUnderrepresented PopulationsUnited States National Institutes of HealthUniversitiesViral GastroenteritisWeaningWomanWorkbiobankbiorepositorybreast feeding infantbreastfeeding infantburden of diseaseburden of illnesscareercareer developmentcohortcomplementationdevelop a vaccinedevelop vaccinesdevelopment of a vaccinedevelopmentaldigestive tract microbiomedisease burdenearly childhoodenteral infectionenteric infectionenteric microbial communityenteric microbiomeenteric microbiotaenteric pathogen infectionenteropathogen infectionenteropathogenic infectionepidemiologicepidemiologicalfamily medicinegastrointestinal microbial floragastrointestinal microbiomeglobal healthgut communitygut floragut microbe communitygut microbial communitygut microbial compositiongut microbial consortiagut microbiomegut microbiome of infantgut microbiotagut microbioticgut microfloragut-associated microbiomehuman milk oligosaccharidesinfant gut microbiomeinfected with enteropathogeninterdisciplinary approachintestinal biomeintestinal epitheliumintestinal floraintestinal infectionintestinal microbiomeintestinal microbiotaintestinal microfloraintestinal tract microfloraintestine infectionkidslactatinglactationalmaternal milkmaternal serummicrobiome community compositionmicrobiome compositionmicrobiome species compositionmicrobiome structuremultidisciplinary approachneonate gut microbiomenewborn gut microbiomenext generationpathogenpatient oriented researchpatient oriented studypediatricpreventpreventingreceptorskill acquisitionskill developmentskillssocial rolestoolunder representation of groupsunder represented groupsunder represented peopleunder represented populationsunderrepresentation of groupsunderrepresented peoplevaccine developmentyoungster
Description preview
ABSTRACT
This K24 renewal builds upon the successful clinical research and mentorship performed by the candidate,
Sylvia Becker-Dreps, MD, MPH. As a natural extension of Dr. Becker-Dreps’ previous work on human norovirus
(NoV), this proposal expands her research skillset to investigate maternal protection against NoV in early
childhood.…
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