grant

Uncovering the biological drivers of Aedes aegypti vector competence

Organization CONNECTICUT AGRICULTURAL EXPERIMENT STALocation NEW HAVEN, UNITED STATESPosted 5 Feb 2026Deadline 31 Jan 2028
NIHUS FederalResearch GrantFY202621+ years oldA. aegyptiAdes aegyptiAdultAdult HumanAe. AegyptiAedes aegyptiAlpha VirusArboviralArbovirusesArthropod VectorsArthropod-Borne VirusesAssayBayesian ModelingBayesian adaptive designsBayesian adaptive modelsBayesian belief networkBayesian belief updating modelBayesian frameworkBayesian hierarchical modelBayesian network modelBayesian nonparametric modelsBayesian spatial data modelBayesian spatial image modelsBayesian spatial modelsBayesian statistical modelsBayesian tracking algorithmsBioassayBiologicalBiological AssayBreakbone Fever VirusCHIKVCHIKV infectionChikungunya virusCommunitiesCompetenceCulicidaeDENVDENV infectionDataDengue InfectionDengue VirusDengue fever virusDengue virus infectionDevelopmentDietDoseExpenditureExposure toFlaviviridaeFlavivirusFutureGeneticGenotypeGoalsGroup A ArbovirusesGroup B ArbovirusHealthHumanHydrogen OxideInfectionInterventionLaboratoriesLarvaMapsMeasuresMediatingMethodsMicrobeModern ManMosquito ControlMosquitoesOrthoflavivirusOutcomePhenotypePredispositionProcessPublic HealthQTLQuantitative Trait LociSamplingSeriesSerotypingSourceStandardizationStructureSusceptibilitySystemTemperatureTestingTherapeuticTogaviridaeTogavirusesTransmissionVaccinesVariantVariationViralViral GeneticsVirusWaterYellow fever virusZIKVZika Virusadulthoodarthropod transmissionarthropod transmittedarthropod-bornearthropodbornebiologicchikungunya infectionchikungunya virus infectioncommunity microbesconditioningdengue viral infectiondensitydevelopmentaldietsdisease riskdisorder riskexperimentexperimental researchexperimental studyexperimentshuman diseasehuman pathogeninfected with CHIKVinfected with chikungunyainfection ratemicrobe communitymicrobial communitymicrobiomemicrobiome community compositionmicrobiome compositionmicrobiome species compositionmicrobiome structuremicroorganism communitynovelpathogenpolymicrobial communityrate of infectionspatial and temporalspatial temporalspatiotemporaltraittransmission processvectorvector competencevectorial competencevirus geneticszikav
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Brackney & Steven
Abstract:

Aedes aegypti mosquitoes are the primary vector for numerous arthropod-borne (arbo) viruses

including dengue virus (DENV; Flaviviridae, Flavivirus), Zika virus (ZIKV; Flaviviridae, Flavivirus), chikungunya

virus (CHIKV; Togaviridae, Alphavirus) and yellow fever virus (YFV; Flaviviridae, Flavivirus). These arboviruses…

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