grant
UAB-UCSD O'Brien Center for Acute Kidney Injury Research
Organization UNIVERSITY OF ALABAMA AT BIRMINGHAMLocation BIRMINGHAM, UNITED STATESPosted 1 Sept 2023Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025AccelerationAcute Kidney FailureAcute Kidney InsufficiencyAcute Renal FailureAcute Renal InsufficiencyAnimal ModelAnimal Models and Related StudiesAnimal TestingAreaAssayBasic ResearchBasic ScienceBioassayBiological AssayBlood VesselsCOVID crisisCOVID epidemicCOVID pandemicCOVID-19 crisisCOVID-19 epidemicCOVID-19 eraCOVID-19 global health crisisCOVID-19 global pandemicCOVID-19 health crisisCOVID-19 pandemicCOVID-19 periodCOVID-19 public health crisisCOVID-19 yearsCapitalCell BodyCell LineCellLineCellsChronic Kidney FailureChronic Renal DiseaseChronic Renal FailureCommunitiesCore FacilityCountryCreatinineDysfunctionEducationEducational ActivitiesEducational aspectsEnvironmentEvaluationFacultyFeedbackFemaleFosteringFunctional disorderGoalsHospital AdmissionHospitalizationHospitalsHumanHuman ResourcesIn VitroIntermediary MetabolismInvestigatorsIschemiaIschemia-Reperfusion InjuryKidneyKidney GraftingKidney TransplantationKidney TransplantsKidney Urinary SystemKnowledgeLength of StayLiquid substanceManpowerMetabolicMetabolic ProcessesMetabolismMethodologyMethodsMicropunctureMissionModern ManMorbidityMorbidity - disease rateNephronsNumber of Days in HospitalOperative ProceduresOperative Surgical ProceduresOxygen ConsumptionPatientsPeer ReviewPhysiologicPhysiologicalPhysiologyPhysiopathologyPreventiveProceduresProcessProductionPublicationsQuality ControlR-Series Research ProjectsR01 MechanismR01 ProgramRenal CellRenal GraftingRenal TransplantationRenal TransplantsRenal functionReperfusion DamageReperfusion InjuryResearchResearch ActivityResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearch ResourcesResearchersResource SharingResourcesRodentRodent ModelRodentiaRodents MammalsSARS-CoV-2 epidemicSARS-CoV-2 global health crisisSARS-CoV-2 global pandemicSARS-CoV-2 pandemicSARS-coronavirus-2 epidemicSARS-coronavirus-2 pandemicSamplingScientific PublicationSepsisServicesSevere Acute Respiratory Syndrome CoV 2 epidemicSevere Acute Respiratory Syndrome CoV 2 pandemicSevere acute respiratory syndrome coronavirus 2 epidemicSevere acute respiratory syndrome coronavirus 2 pandemicStrains Cell LinesSurgicalSurgical InterventionsSurgical ProcedureTechnical ExpertiseTechniquesTechnologyTrainingTranslationsTransplantationTubularTubular formationUriniferous Tubeacute kidney injuryanimal imaginganimal model developmentcare resourcescareerchronic kidney diseasecoronavirus disease 2019 crisiscoronavirus disease 2019 epidemiccoronavirus disease 2019 global health crisiscoronavirus disease 2019 global pandemiccoronavirus disease 2019 health crisiscoronavirus disease 2019 pandemiccoronavirus disease 2019 public health crisiscoronavirus disease crisiscoronavirus disease epidemiccoronavirus disease pandemiccoronavirus disease-19 global pandemiccoronavirus disease-19 pandemiccultured cell linedesigndesigningfield based datafield learningfield studyfield testfluidhealth care resourceshemodynamicshospital dayshospital length of stayhospital stayhuman diseasehuman modelin vivo Modelinnovateinnovationinnovativeinsightinterestkidney cellkidney functionkidney txliquidmeetingmeetingsmembermodel of animalmodel of humanmortalitymouse modelmurine modelnovelpathophysiologypersonnelpre-clinicalpre-clinical studypreclinicalpreclinical studyrenalrenal tubular reabsorptionsevere acute respiratory syndrome coronavirus 2 global health crisissevere acute respiratory syndrome coronavirus 2 global pandemicskillssurgerytechnical skillstherapeutic evaluationtherapeutic testingtooltranslationtransplantvascularweb sitewebsite♀
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Pre-Clinical Core
Small animal models of human disease have provided important insights into renal pathophysiological processes and are an important preclinical resource to test therapeutic and preventive approaches in acute kidney injury (AKI). The specific aims of the Pre-Clinical Core (Core B) are to:
Aim 1. Provide the facilities and skills…
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