grant
Treatment-Related Cardiotoxicity Risk Prediction for Breast Cancer Patients with a Multimodal AI-based System
Organization OHIO STATE UNIVERSITYLocation Columbus, UNITED STATESPosted 23 Jun 2025Deadline 31 May 2030
NIHUS FederalResearch GrantFY2025AI basedAI botAI language modelsAI model trainingAI systemAI trainingAddressAfter CareAfter-TreatmentAftercareAnthracyclineArrhythmiaArtificial IntelligenceArtificial intelligence model trainingBiologicalBreast CancerBreast Cancer PatientBreast Cancer TreatmentBreast Tumor PatientBreathingCancer PatientCardiac ArrhythmiaCardiac ToxicityCardiotoxicCardiotoxicityCardiovascular DiseasesCause of DeathCell Communication and SignalingCell SignalingClinicalCollectionCommunitiesComplementComplement ProteinsComputer ReasoningDataData BasesData CollectionData SetData Storage and RetrievalDatabasesDecision MakingDiagnostic SensitivityDiagnostic testsDoseEarly DiagnosisEarly treatmentElectronic Health RecordEventExclusion CriteriaFaceFutureGoalsGuidelinesHealthHealth Care TechnologyHealth TechnologyHeart ArrhythmiasHeart failureHereditaryHistoryHomeHospitalsHumanIatrogenic CancerImmune mediated therapyImmunologically Directed TherapyImmunotherapyInheritedInterventionInterviewIntracellular Communication and SignalingLabelLinkMachine IntelligenceMachine LearningMalignant Breast NeoplasmModalityModern ManMyocarditisNational Institutes of HealthNatureNon-MalignantOnset of illnessPatient Self-ReportPatientsPhysiciansPhysiologicPhysiologicalPredicting RiskPrediction of Response to TherapyRecording of previous eventsReportingResearchRespiratory AspirationRespiratory InspirationRiskRisk AssessmentRisk ReductionSelection for TreatmentsSelf-ReportSignal TransductionSignal Transduction SystemsSignalingStatistical Data AnalysesStatistical Data AnalysisStatistical Data InterpretationStructureSurvey InstrumentSurveysSurvival RateSymptomsSystemTherapy Related Malignant NeoplasmTherapy Related Malignant TumorTherapy-Associated CancersTherapy-Related CancerTrainingTransformer language modelTreatment-Associated CancerTreatment-Related CancerUnited States National Institutes of HealthUpdateVisitVoiceWorkactive methodactive techniqueactive treatmentanti-cancer treatmentartificial intelligence basedartificial intelligence language modelsartificial intelligence trainingbiologicbiological signal transductionbody sensorbody worn sensorcardiac failurecardiac inflammationcardiovascular disorderchat botchatbotchemotherapyclinical decision-makingcomplementationcomputer based predictionconversational AIconversational agentconversational botdashboarddata analytics dashboarddata basedata dashboarddata de-identificationdata deidentificationdata managementdata modalitiesdata retrievaldata storagede-identified datadeidentified datadesigndesigningdigital healthdisease onsetdisorder onsetearly detectionearly therapyelectronic health care recordelectronic health medical recordelectronic health plan recordelectronic health registryelectronic medical health recordexperimentexperimental researchexperimental studyexperimentsfacesfacialforecasting riskhealth dataheart rate variabilityhistorieshomesimmune therapeutic approachimmune therapeutic interventionsimmune therapeutic regimensimmune therapeutic strategyimmune therapyimmune-based therapiesimmune-based treatmentsimmuno therapyimprovedimproved outcomeindividuals with breast cancerinnovateinnovationinnovativeinsightinspirationinteractive data visualizationinteractive visualizationinterestlarge language modellarge scale language modelmachine based learningmachine learning based modelmachine learning modelmalignant breast tumormassive scale language modelsmeetingmeetingsmortalitymulti-modal datamulti-modal datasetsmulti-modalitymultimodal datamultimodal datasetsmultimodalitynonmalignantnovelpatients with breast cancerperson with breast cancerpost treatmentpredict riskpredict riskspredict therapeutic responsepredict therapy responsepredicted riskpredicted riskspredicting riskspredictive modelingpredictive riskpredicts riskrecruitreduce riskreduce risksreduce that riskreduce the riskreduce these risksreduces riskreduces the riskreducing riskreducing the riskrisk predictionrisk prediction algorithmrisk prediction modelrisk prediction systemrisk prediction toolrisk predictionsrisk-reducingselection of treatmentstandard carestandard treatmentstatistical analysistherapy predictiontherapy selectiontreatment predictiontreatment response predictiontreatment selectiontumorusabilityuser-friendlyvisual dashboardvisualization dashboardwearablewearable biosensorwearable devicewearable electronicswearable sensorwearable sensor technologywearable systemwearable technologywearable toolwearablesweb based dashboardweb dashboard
Description preview
Abstract
Anti-tumor therapies (e.g., anthracyclines, biologic, and immunotherapy) are the standard treatments for most
breast cancer patients, and dramatically improve survival rates. However, up to 20% of breast cancer patients
treatment with these therapies will develop some form of serious cardiovascular disease (CVD), such as heart
failure,…
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