grant

Translational Research to Accelerate Interventions for Fetal Alcohol Spectrum Disorders: Evaluation of Physical Activity at Basic and Clinical Levels

Organization SAN DIEGO STATE UNIVERSITYLocation SAN DIEGO, UNITED STATESPosted 1 May 2024Deadline 30 Apr 2029
NIHUS FederalResearch GrantFY20260-11 years oldASDAbsolute ethanolAccelerationAccelerometerAddressAdolescentAdolescent YouthAerobic ActivityAerobic ExerciseAerobic TrainingAerobic fitnessAffectAlcohol Chemical ClassAlcoholsAmmon HornAnimal ModelAnimal Models and Related StudiesAnxietyAttentionAttenuatedAutismAutistic DisorderAwardBasic ResearchBasic ScienceBehavioralBehavioral ParadigmBlood SampleBlood specimenBrainBrain Nervous SystemChildChild YouthChildhoodChildren (0-21)ClinicalClinical DataClinical ResearchClinical SciencesClinical StudyClinical TreatmentCognitionCognitiveCommon Rat StrainsCornu AmmonisDataData SetDevelopmentDiagnosisDiseaseDisorderDysfunctionETOHEarly Infantile AutismEmotionalEncephalonEthanolEthyl AlcoholEvaluationExerciseFASDFetal Alcohol ExposureFetal Alcohol Spectrum DisorderFetal ETOH ExposureFetal Ethanol ExposureFetal alcohol effectsFunctional disorderFundingGoalsGrain AlcoholHealthHealth BenefitHippocampusHistoryHyperactivityImmuneImmune MarkersImmunesImmunologic MarkersImpairmentIn Utero Alcohol ExposureIn Utero ETOH ExposureIn Utero Ethanol ExposureIndividualInfantile AutismInterventionIntervention StudiesInvestigatorsKanner's SyndromeLanguageLearningLifeLocomotor ActivityLongitudinal StudiesLongitudinal SurveysMeasuresMemoryMental DepressionMental HealthMental HygieneMentorshipMethylcarbinolModelingMolecularMotorMotor ActivityNIAAANational Institute on Alcohol Abuse and AlcoholismNational Institutes of HealthNeural DevelopmentNeuranatomiesNeuranatomyNeuroanatomiesNeuroanatomyNeurocognitionNeurodevelopmental DisorderNeuroimmuneNeurological Development DisorderOutcomePatternPhysical activityPhysiopathologyPopulationPreclinical dataPrenatal Alcohol ExposurePrenatal ETOH ExposurePrenatal Ethanol ExposurePsychological HealthPublic HealthQuestionnairesRatRats MammalsRattusRecording of previous eventsResearchResearch PersonnelResearch SupportResearch TrainingResearchersRodent ModelRunningSamplingStrategic PlanningSurvey InstrumentSurveysSymptomsTeratogenic effectsTestingTherapeuticTrainingTranslatingTranslational ResearchTranslational ScienceUnited StatesUnited States National Institutes of HealthVariantVariationYouthYouth 10-21accelerometryactivity monitoractivity trackeralcohol-exposed pregnancyanxiety-like behaviorassess effectivenessattenuateattenuatesautism spectral disorderautism spectrum disorderautistic spectrum disorderbehavior testbehavioral testcareerclinical interventionclinical relevanceclinical therapyclinically relevantcognitive developmentcognitive functioncohortdepressiondetermine effectivenessdevelopmentaleffectiveness assessmenteffectiveness evaluationemotional functioningevaluate effectivenessexamine effectivenessexecutive controlexecutive functionexercise interventionexperienceexposed to alcohol prenatallygestation ETOH exposuregestation alcohol exposuregestation ethanol exposuregestational ethanol exposurehippocampalhistorieshuman dataimmune-based biomarkersimmunological biomarkersimmunological markersimprovedimproved outcomeinnovateinnovationinnovativeintervention researchinterventional researchinterventional studyinterventions researchjuvenilejuvenile humankidslife spanlifespanlong-term studylongitudinal outcome studieslongitudinal research studymodel of animalneurobehavioralneurodevelopmentneurodevelopmental diseaseneurogenesisneuropathologicneuropathologicalneuropathologyneuroprotectionneuroprotectiveneurotrophic factorneurotrophinneutrophinpathophysiologypediatricphysical activity interventionpost interventionpre-clinicalpre-clinical researchpreclinicalpreclinical findingspreclinical informationpreclinical researchpregnancy ETOH exposurepregnancy alcohol exposurepregnancy ethanol exposureprenatal alcohol effectprenatally alcohol exposedprenatally exposed to alcoholprocessing speedprogramsspatial memorytranslation researchtranslational investigationtranslational investigatortranslational neurosciencetranslational researchertranslational scientisttrial regimentrial treatmentyoungsteryouth age
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PROJECT SUMMARY
Although identified over 50 years ago, there are a limited number of interventions for fetal alcohol spectrum
disorders (FASD), the leading known preventable neurodevelopment disorders in the U.S. Neuropathology
associated with prenatal alcohol exposure (PAE) alters behavioral, cognitive, and emotional functions that
persistent in…

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Translational Research to Accelerate Interventions for Fetal Alcohol Spectrum Disorders: Evaluation of Physical Activity | Dev Procure