grant
Translational Oncology Research Program
Organization UNIVERSITY OF KENTUCKYLocation LEXINGTON, UNITED STATESPosted 8 Jul 2013Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY20254E-BP1AddressAnti-Cancer AgentsAntineoplastic AgentsAntineoplastic DrugsAntineoplasticsAppalachiaAppalachianAppalachian RegionAreaAwardBasic ResearchBasic ScienceBiologic ModelsBiological MarkersBiological ModelsBreastCCSGCancer BurdenCancer CenterCancer Center Support GrantCancer ControlCancer Control ScienceCancer DrugCancer PatientCancer TreatmentCancersCatchment AreaCenter for Cancer ResearchClinicClinicalClinical FacultyClinical Nurse EducatorClinical OncologyClinical TrialsClinical Trials NetworkCollaborationsColorectal CancerCommunitiesCommunity OutreachDNA mutationDataDevelopmentDevicesDietDirect CostsDisparitiesDisparityDrugsEIF4EBP1EIF4EBP1 geneET-CTNEarly Therapeutic-Clinical Trials NetworkEarly identificationElectronicsEnrollmentEnteric HormonesExperimental TherapiesFASNFASN geneFosteringFundingFutureGenetic ChangeGenetic defectGenetic mutationGenomicsGoalsGold CompoundsIncidenceIndividualInfrastructureInstitutionInterdisciplinary ResearchInterdisciplinary StudyInternationalIntestinal HormonesInvestigational DrugsInvestigational New DrugsInvestigational TherapiesInvestigational TreatmentsInvestigatorsKentuckyLeadLeadershipMGC14367MGC15706Malignant Neoplasm TherapyMalignant Neoplasm TreatmentMalignant NeoplasmsMalignant TumorManuscriptsMediatorMedicationMissionModel SystemMolecularMolecular TargetMulti-Institutional Clinical TrialMulti-center clinical trialMulti-site clinical trialMulticenter clinical trialMultidisciplinary CollaborationMultidisciplinary ResearchMultisite clinical trialMutationNCI Center for Cancer ResearchNCI OrganizationNGS MethodNGS systemNational Cancer BurdenNational Cancer InstituteNational Institutes of HealthNatural ProductsNeoplastic Disease Chemotherapeutic AgentsNurse EducatorNursing FacultyNursing Staff DeveloperNursing Staff Development SpecialistOA-519ObesityOncologyOncology CancerParticipantPatient outcomePatient-Centered OutcomesPatient-Focused OutcomesPatientsPb elementPeer ReviewPharmaceutical PreparationsPhasePhase I StudyPhenotypePopulationPreclinical dataProstateProstate GlandProstatic GlandPublic PolicyPublicationsPublishingRadiopharmaceutical CompoundRadiopharmaceuticalsResearchResearch PersonnelResearch PriorityResearch ResourcesResearchersResourcesRoleRuthenium CompoundsScienceScientific PublicationStrategic PlanningStructureTherapeuticTherapeutic AgentsTherapeutic InterventionTranslatingTranslationsTumor-Specific Treatment AgentsUnited States National Institutes of HealthUniversitiesValidationadiposityanti-cancer druganti-cancer therapyanti-cancer treatmentbio-markersbiologic markerbiomarkercancer carecancer preventioncancer therapycancer-directed therapycellular oncologyclinical developmentclinical relevanceclinical translationclinical trial enrollmentclinically relevantclinically translatablecollegecollegiatecommunity engagementcorpulencecross curricular programcross disciplinary educational programcross disciplinary programdepositorydesigndesigningdevelopmentaldietsdisparities in racedisparity due to racedisparity in ethnicdrug repositioningdrug repurposingdrug/agentearly clinical trialearly phase clinical trialelectronicelectronic deviceengagement with communitiesenrollethnic based disparityethnic disadvantageethnic disparityethnic inequalityethnic inequityethnicity disparityexperimental therapeutic agentsexperimental therapeuticsgenome mutationgenome resourcegenomic data resourcegenomic resourcegenomic sequencing resourceheavy metal Pbheavy metal leadinequality due to raceinequity due to raceinhibitorinsightinter-institutionalintervention programintervention therapyinvestigator-initiated trialmalignancymembermolecular oncologymortalitynaturally occurring productneoplasm/cancernew anti-cancer agentnew anticancer agentnew anticancer drugnew antineoplasticnew cancer drugnew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapeuticsnew therapynew therapy approachesnew treatment approachnew treatment strategynext gen sequencingnext generation sequencingnext generation therapeuticsnextgen sequencingnovelnovel anti-cancer agentnovel anti-cancer drugnovel anticancer agentnovel anticancer drugnovel antineoplasticnovel cancer drugnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapeuticsnovel therapynovel therapy approachoncology programpatient oriented outcomesphase 1 studypre-clinicalpre-clinical developmentprecision medicineprecision-based medicinepreclinicalpreclinical developmentpreclinical findingspreclinical informationprogramsrace based disparityrace based inequalityrace based inequityrace disparityrace related disparityrace related inequalityrace related inequityracial disparityracial inequalityracial inequityracially unequalradioactive drugsradiotherapeutic drugsrecruitrepositoryrepurposing agentrepurposing medicationsocial roletranslationtranslational goaltranslational missiontranslational oncologytranslational pipelinetranslational spectrumtranslational studytreatment trialtumorvalidationswork groupworking group
Description preview
PROJECT SUMMARY/ABSTRACT
The Markey Cancer Center’s (MCC) Translational Oncology (TO) Research Program is scientifically focused on identifying novel targets, discovering new anticancer agents and devices, and leading catchment-relevant clinical trials to decrease cancer incidence and mortality in Kentucky and the nation. The overarching theme of…
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