grant

Translating Individual-level Risks and Preferences Into Personalized Blood Pressure Target Decisions

Organization UNIVERSITY OF CALIFORNIA AT DAVISLocation DAVIS, UNITED STATESPosted 1 Feb 2025Deadline 31 Jan 2030
NIHUS FederalResearch GrantFY202621+ years oldAcute Kidney FailureAcute Kidney InsufficiencyAcute Renal FailureAcute Renal InsufficiencyAdultAdult HumanAffectAwardBP reductionBiostatistical MethodsBlood PressureCVD preventionCalibrationCardiovascular DiseasesCause of DeathCenter for Translational Science ActivitiesCessation of lifeChronicClinicalClinical InvestigatorClinical SciencesClinical TrialsCognitive DiscriminationDataDeathDecision AidDecision MakingDiabetes MellitusDiscriminationElectronic Health RecordEpidemiologyEventFaintingFundingGoalsGuidelinesHealthHeterogeneityHomeHypertensionHypotensionIndividualIndividualized risk predictionInstitutionInternationalIntervention TrialInterventional trialInvestigatorsK23 AwardK23 MechanismK23 ProgramKidney DiseasesKnowledgeLow Blood PressureMeasuresMedical HistoryMentored Patient-Oriented Research Career Development AwardMentored Patient-Oriented Research Career Development Award (K23)MentorsMentorshipModelingNephropathyOutcomeParticipantPatient Outcomes AssessmentsPatient PreferencesPatient Reported MeasuresPatient Reported OutcomesPatient riskPatientsPersonal Medical HistoryPersonal Medical History EpidemiologyPersonalized medical approachPersonsPositionPositioning AttributePredicting RiskPreventative strategyPrevention strategyPreventive strategyProcessProviderPublic HealthRandomization trialRecommendationRenal DiseaseResearchResearch PersonnelResearchersRespondentRiskRisk EstimateSamplingScienceSerious Adverse EventSevere Adverse EventStatistical MethodsSurvey InstrumentSurveysSyncopeTestingTrainingTranslatingTreatment outcomeValidationVariantVariationVascular Hypertensive DiseaseVascular Hypertensive DisorderVascular Hypotensive DisorderWorkacceptability and feasibilityacute kidney injuryadulthoodbehavioral clinical trialblood pressure interventionblood pressure reductioncardiac disease preventioncardiovascular disease epidemiologycardiovascular disease preventioncardiovascular disease riskcardiovascular disordercardiovascular disorder epidemiologycardiovascular disorder preventioncardiovascular disorder riskcardiovascular epidemiologycardiovascular riskcardiovascular risk factorcare as usualcareerclinical decision-makingcomputer based predictioncustomized therapycustomized treatmentdesigndesigningdiabetesdigital healthelectronic health care recordelectronic health medical recordelectronic health plan recordelectronic health registryelectronic medical health recordepidemiologicepidemiologicalexperienceforecasting riskhigh blood pressurehomeshyperpiesiahyperpiesishypertensive diseasehypertensive disorderindividualized approachindividualized clinical decisionindividualized decisionindividualized medicineindividualized patient treatmentindividualized predictionsindividualized therapeutic strategyindividualized therapyindividualized treatmentinnovateinnovationinnovativeinstrumentkidney disorderlower BPlower blood pressurelowers blood pressuremachine learning based methodmachine learning methodmachine learning methodologiesmortalitynon-diabeticnondiabeticnovelpatient oriented researchpatient oriented studypatient specific therapiespatient specific treatmentpatient-clinician communicationpatient-doctor communicationpatient-provider communicationpersonalized approachpersonalized clinical decisionpersonalized data-driven decisionpersonalized decisionpersonalized predictionspersonalized risk predictionpilot trialprecision approachpredict riskpredict riskspredicted riskpredicted riskspredicting riskspredictive modelingpredictive riskpredicts riskpreferencerandomized trialrecruitreduce BPreduce blood pressurereduction in BPreduction in blood pressurerenal disorderrisk predictionrisk predictionsserious adverse experienceserious adverse reactionshared decision makingskill acquisitionskill developmentskillsstatistic methodstailored approachtailored medical treatmenttailored therapytailored treatmenttooltranslational research centertranslational sciences centertreatment as usualtreatment effecttreatment strategyunique treatmentusual carevalidations
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PROJECT SUMMARY
Simon Ascher, MD, MPH is establishing himself as a clinical investigator in patient-oriented research that

focuses on individualizing clinical decision-making in hypertension. This K23 award will provide the necessary

training for Dr. Ascher to successfully transition to an independent investigator and achieve the following goals:…

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Translating Individual-level Risks and Preferences Into Personalized Blood Pressure Target Decisions — UNIVERSITY OF CAL | Dev Procure