grant

Tissue Procurement Center (TPC) Supporting the Somatic Mosaicism across Human Tissues (SMaHT) Network

Organization NATIONAL DISEASE RESEARCH INTERCHANGELocation PHILADELPHIA, UNITED STATESPosted 1 May 2023Deadline 30 Apr 2028
NIHUS FederalResearch GrantFY2025AddressAuthorizationAuthorization documentationAutopsyBiologyBoard CertificationBody SystemBody TissuesBrainBrain Nervous SystemCell BodyCellsChildren's HospitalClinicalCollectionCommunitiesDNA AlterationDNA Sequence AlterationDataData AnalysesData AnalysisDevelopmentDiagnosisDiseaseDisorderELSIEncephalonEthical AnalysesEthical AnalysisEvaluationFactor AnalysesFactor AnalysisFaithFamilyFocus GroupsGene ExpressionGenerationsGenetic AlterationGenetic DiversityGenetic VariationGenotypeGrantHealth ServicesHumanHuman FigureHuman bodyImageIndividualInfrastructureInstitutionIntentionInterviewInvestigationInvestigatorsLeadMarylandMedulla SpinalisMethodologyModern ManMosaicismNational Institutes of HealthOrganOrgan ProcurementsOrgan SystemPathologicPathologyPb elementPediatric HospitalsPermissionProceduresProcessPsychologistQuality ControlRecoveryReliability of ResultsReportingReproducibility of FindingsReproducibility of ResultsResearchResearch DesignResearch PersonnelResearch ResourcesResearchersResourcesSamplingSequence AlterationSmaHTSomatic Mosaicism across Human TissuesSomatic MutationSpinal CordStructureStudy TypeTechnical ExpertiseTissue BanksTissue CollectionTissue DonationsTissue ProcurementsTissue SampleTissue imagingTissue repositoryTissuesTrainingUnited States National Institutes of HealthUniversitiesbiobankbiorepositorycommunity engagementdata interpretationdeceased donordeceased organ donorsdesigndesigningdevelopmentalempowermentengagement with communitiesethical legal and socialethical, legal, and social implicationexperienceexperimental analysisgenomic alterationheavy metal Pbheavy metal leadhuman diseasehuman tissueimaginginsightmosaic diseasesmosaic disordersnecropsynew approachesnovel approachesnovel strategiesnovel strategyoperationoperationsposthumous donorsposthumous organ donorpostmortemprogramssomatic variantstudy designsuccesstech developmenttechnical skillstechnology developmenttool developmentwhole slide imaging
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The Somatic Mosaicism across Human Tissues (SMaHT) network project will establish the first comprehensive public resource correlating genetic variation due to somatic mosaicism in human tissues from all development layers in the human body. The SMaHT Network will have multiple centers to support the advancement of three primary initiatives: 1)…

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Tissue Procurement Center (TPC) Supporting the Somatic Mosaicism across Human Tissues (SMaHT) Network — NATIONAL DISEASE | Dev Procure