grant
Time course and predictors of progression to postpartum prediabetes and type 2 diabetes in HIV: a prospective longitudinal study of low-income Indian women
Organization WEILL MEDICAL COLL OF CORNELL UNIVLocation NEW YORK, UNITED STATESPosted 1 May 2024Deadline 28 Feb 2029
NIHUS FederalResearch GrantFY2025(TNF)-αAIDS VirusAccelerationAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAdult-Onset Diabetes MellitusAffectApoplexyAsian FemalesAsian WomenBMIBMI percentileBMI z-scoreBeta CellBiometricsBiometryBiostatisticsBlood SerumBody Weight decreasedBody mass indexBrain Vascular AccidentCachectinCardiac infarctionCell FunctionCell PhysiologyCell ProcessCellular FunctionCellular PhysiologyCellular ProcessCellular StressCellular Stress ResponseCellular injuryCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCessation of lifeClinical TrialsCollaborationsConduct Clinical TrialsCountryCox Proportional Hazards ModelsD-GlucoseDataDeathDevelopmentDevelopment PlansDextroseDiabetes MellitusDiabetes preventionDrug TherapyDysfunctionEnvironmentEpidemiologyEquationFastingFatsFatty acid glycerol estersFree Fatty AcidsFunctional disorderFutureGestationGestational DiabetesGestational Diabetes MellitusGlucoseGoalsGovernmentHIVHIV InfectionsHTLV-III InfectionsHTLV-III-LAV InfectionsHuman Immunodeficiency VirusesHuman T-Lymphotropic Virus Type III InfectionsHumulin RIndiaInsulinInsulin CellInsulin ResistanceInsulin Secreting CellInterventionIntervention StudiesInvestigatorsKetosis-Resistant Diabetes MellitusKidney DiseasesLAV-HTLV-IIILeadershipLifestyle TherapyLiteratureLong-term cohort studyLong-term prospective studiesLongitudinal StudiesLongitudinal cohort studyLow incomeLow-resource areaLow-resource communityLow-resource environmentLow-resource regionLow-resource settingLymphadenopathy-Associated VirusMacrophage-Derived TNFMaturity-Onset Diabetes MellitusMeasuresMedicineMentorsMentorshipMonocyte-Derived TNFMyocardial InfarctMyocardial InfarctionNIDDMNephropathyNon obeseNon-Insulin Dependent DiabetesNon-Insulin-Dependent Diabetes MellitusNonesterified Fatty AcidsNoninsulin Dependent DiabetesNoninsulin Dependent Diabetes MellitusNonobeseNovolin ROGTTOral Glucose Tolerance TestOver weightOverweightPancreatic beta CellPancreatic β-CellPathogenesisPersonsPharmacological TreatmentPharmacotherapyPhysiciansPhysiopathologyPopulationPost-partum WomenPostpartum PeriodPostpartum WomenPrediabetesPrediabetes syndromePrediabetic StatePredispositionPregnancyPregnancy-Induced DiabetesPregnant WomenPreparationPreventionPrevention GuidelinesProductionPublicationsQuetelet indexRegular InsulinRenal DiseaseResearchResearch PersonnelResearchersResistanceResource-constrained areaResource-constrained communityResource-constrained environmentResource-constrained regionResource-constrained settingResource-limited areaResource-limited communityResource-limited environmentResource-limited regionResource-limited settingResource-poor areaResource-poor communityResource-poor environmentResource-poor regionResource-poor settingRiskScientific PublicationScientistSerumSlow-Onset Diabetes MellitusSouth AsianStable Diabetes MellitusStrokeStructure of beta Cell of isletSubcellular ProcessSusceptibilityT2 DMT2DT2DMTNFTNF ATNF AlphaTNF geneTNF-αTNFATNFαTestingTimeTrainingTumor Necrosis FactorTumor Necrosis Factor-alphaType 2 Diabetes MellitusType 2 diabetesType II Diabetes MellitusType II diabetesVirus-HIVVisceral fatWeight LossWeight ReductionWomanWorkWorld Health Organizationadult onset diabetesafter gestational diabetesbasebasesbody weight lossbrain attackcardiac infarctcareer developmentcell damagecell injurycell stresscellular damagecerebral vascular accidentcerebrovascular accidentcohortcoronary attackcoronary infarctcoronary infarctiondamage to cellsdesigndesigningdevelopmentaldiabetesdiabetes riskdrug interventiondrug treatmentefficacy testingepidemiologicepidemiologicalexpectant motherexpectant womenexpecting motherexpecting womenfastedfastsfollowing gestational diabetesgestational diabetes historyglucose tolerancehazardheart attackheart infarctheart infarctionhigh riskhigh risk grouphigh risk individualhigh risk peoplehigh risk populationindexingindividuals who are pregnantinflammation markerinflammatory markerinjury to cellsinsulin resistantinsulin toleranceintervention researchinterventional researchinterventional studyinterventions researchketosis resistant diabeteskidney disorderlife style interventionlifestyle interventionlong-term studylongitudinal outcome studieslongitudinal, prospective studymaturity onset diabetesmedical collegemedical schoolsobese individualsobese peopleobese personobese populationobese subjectspancreas beta cellpancreas β cellpancreatic b-cellpathophysiologypeople who are pregnantpharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticspost-partumpost-partum weightpostpartum weightpre-diabetespre-diabeticprediabeticpregnancy diabetespregnant femalespregnant motherspregnant peoplepregnant populationspreparationspreventpreventingprogression riskrenal disorderresistantschool of medicineskillsstrokedstrokesthose who are pregnanttype 2 DMtype II DMtype two diabeteswomen who are pregnantwt-lossyoung womanβ-cellβ-cellsβCell
Description preview
PROJECT SUMMARY & ABSTRACT
Candidate. Dr. Puja Chebrolu is a physician-scientist who has spent the past five years conducting research
on HIV and diabetes in India. She has conducted longitudinal research, developed strong scientific
collaborations with Indian scientists, trained an Indian research team, and authored 10 publications. She has…
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