grant
The role of heterogeneity among extraocular motor neurons for eye movement control
Organization NEW YORK UNIVERSITY SCHOOL OF MEDICINELocation NEW YORK, UNITED STATESPosted 1 Sept 2025Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY2025Activities of Daily LivingActivities of everyday lifeAddressAnatomic SitesAnatomic structuresAnatomyAssayBehaviorBehavioralBioassayBiological AssayBrachydanio rerioCell NucleusCephalicCharacteristicsClassificationCranialDanio rerioDataDate of birthDevelopmentDiseaseDisorderDysfunctionEyeEye MovementsEyeballFiberFunctional disorderGeneticGoalsHealthHeterogeneityHistoryImageImpaired healthIndividualKnowledgeLabelLesionLinkLocomotionLogicMeasuresMedulla SpinalisMethodsMissionModelingMotorMotor CellMotor NeuronsMovementMuscleMuscle FibersMuscle TissueMyotubesNational Institutes of HealthNerve CellsNerve UnitNeural CellNeurocyteNeuronsNeurophysiology - biologic functionNucleusOpticsPerformancePhysiopathologyPopulationPopulation HeterogeneityPositionPositioning AttributePropertyRecording of previous eventsReflexReflex actionResearchRhabdomyocyteRoleSensoryShapesSkeletal FiberSkeletal Muscle CellSkeletal Muscle FiberSkeletal MyocytesSpecific qualifier valueSpecifiedSpinalSpinal CordSystemSystematicsSystems DevelopmentTestingTrainingUnited States National Institutes of HealthVertebrate AnimalsVertebratesVestibularWorkZebra DanioZebra FishZebrafishbody movementdaily living functiondaily living functionalitydefined contributiondevelopmentaldiverse populationsexperimentexperimental researchexperimental studyexperimentsfallsfunctional abilityfunctional capacityheterogeneous populationhistoriesimaginginsightkinematic modelkinematicsmotoneuronmotor controlmuscularneuralneural circuitneural circuitryneural functionneurocircuitryneuronalocular motorocularmotoroculomotoroculovestibular reflexopticaloptogeneticspathophysiologypopulation diversityrecruitresponsesegregationsocial rolesynaptic circuitsynaptic circuitrytoolvertebratavestibo-ocular reflexesvestibular systemvestibulo-occular systemvestibulo-ocular reflexvestibulo-oculomotor reflexvestibuloocular reflexes
Description preview
PROJECT SUMMARY
Developmentally-defined subtypes of motor neurons with specialized anatomical and functional properties
are required for facilitating movement. Exploring the relationships among developmental, anatomical and
functional properties of spinal motor neuron subtypes unveiled fundamental insights into the mechanisms
governing…
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