grant
The mechanistic basis for the ZAP antiviral system targeting viral and cellular RNAs
Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
Description preview
ZAP is an antiviral protein found in most vertebrates that restricts a diverse range of viruses by binding viral RNA to inhibit its translation into viral proteins and target it for degradation. A full understanding of how ZAP inhibits viruses can be used to develop new therapeutic applications. Introducing ZAP binding sites in viral RNA could…
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