grant
The Impact of Positive Airway Pressure (PAP) Therapy on Myocardial Blood Flow in Adults with Obstructive Sleep Apnea at High-Risk of Cardiovascular Disease: The PAP-Flow Study
NIHUS FederalResearch GrantFY202521+ years old65 and older65 or older65 years of age and older65 years of age or more65 years of age or older65+ years65+ years oldAdultAdult HumanAged 65 and OverApneaApplications GrantsAwardBiological MarkersBlood SerumBlood TestsBlood VesselsBlood flowCardiacCardiac AbnormalitiesCardiac ChronotropismCardiovascular DiseasesClinical ResearchClinical StudyClinical TrialsCoronaryDeath RateDevelopmentDiastolic heart failureDisease OutcomeEFRACEchocardiogramEchocardiographyEjection FractionEndotheliumExhibitsFoundationsFunctional ImagingFutureGrant ProposalsHF with preserved ejection fractionHFpEFHeartHeart AbnormalitiesHeart RateHeart failureHematologic TestsHematological TestsHematology TestingHospital AdmissionHospitalizationHourHypoxiaHypoxicImageIndividualInvestigatorsLeftLinkMeasuresMetabolicMicrocirculationMicrovascular DysfunctionMyocardialMyocardiumO elementO2 elementObstructive Sleep ApneaOutcomeOxygenOxygen DeficiencyPETPET ScanPET imagingPETSCANPETTPatientsPersonsPhenotypePhysiologicPhysiologic ImagingPhysiologicalPhysiologyPositionPositioning AttributePositron Emission Tomography Medical ImagingPositron Emission Tomography ScanPositron-Emission TomographyPreventionRad.-PETResearch DesignResearch PersonnelResearchersRiskRisk AssessmentSerumSleepSleep ApneaSleep Apnea SyndromesSleep HypopneaSleep-Disordered BreathingStress TestsStudy TypeSyndrome, Sleep Apnea, ObstructiveTestingTherapeuticTranslational ResearchTranslational ScienceTransthoracic EchocardiographyUnited StatesVascular EndotheliumVascular Smooth MuscleVentricularWorkabove age 65adulthoodafter age 65age 65 and greaterage 65 and olderage 65 or olderageage of 65 years onwardaged 65 and greateraged 65+aged ≥65bio-markersbiologic markerbiomarkercardiac failurecardiac functioncardiac imagingcardiac musclecardiac scanningcardiovascular disease riskcardiovascular disordercardiovascular disorder riskdevelopmentaldisease prognosisdisease prognosticationendothelial dysfunctionexperiencefunction of the heartheart failure with preserved ejection fractionheart failure with preserved systolic functionheart functionheart imagingheart muscleheart scanningheart sonographyhigh riskhuman old age (65+)imagingimprovedindexinginnovateinnovationinnovativemicrovascular complicationsmicrovascular diseasemortality ratemortality ratiomuscle hypertrophynovelover 65 yearsperfusion imagingphysiological imagingpositive airway pressurepositron emission tomographic (PET) imagingpositron emission tomographic imagingpositron emitting tomographypreservationpreserved ejection fraction heart failurepressurerate of changerecruitresponseskillssleep-related breathing disordersmall vessel diseasestudy designtheoriestranslation researchtranslational investigationvascular≥65 years
Description preview
ABSTRACT
New and innovative approaches to studying modifiable mechanisms of heart failure are crucial. Heart failure
impacts approximately 7 million adults in the United States and has a 5-year mortality rate of 42%.
Obstructive sleep apnea (OSA), traditionally assessed by the apnea-hypopnea index (AHI), increases the risk of
heart failure.…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click