grant

The development of a technology-based information support intervention (iSupport) among patients with differentiated thyroid cancer post radioactive iodine therapy

Organization GEORGETOWN UNIVERSITYLocation WASHINGTON, UNITED STATESPosted 2 Mar 2023Deadline 29 Feb 2028
NIHUS FederalResearch GrantFY2026Active Follow-upAddressAdverse Late EffectsAdverse effectsAppointmentBehavior Conditioning TherapyBehavior ModificationBehavior TherapyBehavior TreatmentBehavioralBehavioral Conditioning TherapyBehavioral ModelBehavioral ModificationBehavioral TherapyBehavioral TreatmentCancer PatientCancersCaringCell PhoneCellular PhoneCellular TelephoneCommunicationComputersConditioning TherapyControl GroupsDataDevelopmentDevicesDiagnosisDistressDysfunctionEducationEducation for InterventionEducational InterventionEducational aspectsEndocrineEnrollmentFamilyFocus GroupsFollicular AdenocarcinomaFollicular CarcinomaFollicular Thyroid CancerFollicular Thyroid Gland CancerFollicular thyroid carcinomaFrequenciesFrustrationFunctional disorderGoalsGoldImpairmentIndividualInformation ManagementInstruction InterventionInterventionInterviewKnowledgeLacrimal GlandsLacrimal gland structureLate EffectsLearningMalignant NeoplasmsMalignant Thyroid Gland NeoplasmMalignant TumorMalignant Tumor of the ThyroidMalignant Tumor of the Thyroid GlandMalignant neoplasm of thyroidMeasuresMobile PhonesNasalNasal Passages NoseNoseOn-Line SystemsOnline SystemsOutcomePainPainfulPapillary CarcinomaParticipantPatientsPersonal SatisfactionPersonsPhasePhysiopathologyPopulationProviderRadioactive IodineRandomizedRandomized, Controlled TrialsReportingResearchResearch DesignRespiratory System, Nose, Nasal PassagesSalivarySalivary GlandsSecond CancerSecond Primary CancersSecondary MalignancySecondary Malignant NeoplasmSelf EfficacySleep disturbancesSocial FunctioningStructureStudy TypeSurvival RateSymptom BurdenSymptomsSystemTechnologyTestingThyroid AdenocarcinomaThyroid CancerThyroid Gland Follicular CarcinomaTraining InterventionTreatment EfficacyTreatment Side EffectsTreatment-related side effectsWell-Differentiated Follicular AdenocarcinomaWell-Differentiated Follicular CarcinomaWorkaberrant sleepacceptability and feasibilityactive followupalleviate symptomameliorating symptombehavior interventionbehavioral interventioncancer survivor carecancer survivorship carecare as usualdecrease symptomdesigndesigningdevelop therapydevelopmentaldigital technologydisrupted sleepdisturbed sleepempowermentenrollexperiencefewer symptomsfollow upfollow-upfollowed upfollowupfunction sociallyfunctioning socialgroup interventionhealth related quality of lifeiPhoneimpaired sleepimprovedinstructional interventioninternet-based interventionintervention developmentintervention efficacyirregular sleeplacrimalmalignancymanage symptomneoplasm/cancernovelonline computerparticipant enrollmentpathophysiologypatient enrollmentpatient populationpatient retentionpilot testprimary outcomeradioactive iodine therapyradioactive iodine treatmentradioiodineradioiodine (RAI) treatmentradioiodine therapyradioiodine treatmentrandomisationrandomizationrandomized control trialrandomly assignedreduce symptomsrelieves symptomssecondary cancersecondary outcomeside effectsleep disruptionsleep dysregulationsleep/wake disruptionsleep/wake disturbancesmart phonesmartphonesocial cognitive theorysocial learning theorystudy designsupport toolssurvival outcomesurvivorshipsymptom alleviationsymptom managementsymptom reductionsymptom reliefsymptom treatmentsymptomatic treatmenttechnology interventiontechnology-based interventionstechnology-enabled interventionstechnology-focused interventionstherapeutic efficacytherapy developmenttherapy efficacytooltreat symptomtreatment as usualtreatment developmenttreatment effectunderstudied cancerusabilityusual careweb basedweb siteweb-based interventionwebsitewell-beingwellbeing
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Description preview

Radioactive iodine (RAI) therapy is routinely used among patients diagnosed with differentiated thyroid cancer (DTC), with approximately 76% of patients receiving RAI. Patients with DTC post RAI treatment report extensive short-term and late effects of treatment, symptom burden, and unmet informational needs about treatment-related side effects.…

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