grant
The Center for Phage Pharmaceuticals (Phage Pharm)
Organization STANFORD UNIVERSITYLocation STANFORD, UNITED STATESPosted 1 Apr 2026Deadline 31 Mar 2031
NIHUS FederalResearch GrantFY2026AddressAirway infectionsAlabamaAnimal ModelAnimal Models and Related StudiesAntibiotic AgentsAntibiotic DrugsAntibioticsAntimicrobial ResistanceAssayAtomic MedicineBacteriaBacterial InfectionsBacteriophagesBioassayBiological AssayBusiness-Friendly AtmosphereCFTRCFTR ProteinChronicClinicCollaborationsCommon Rat StrainsCommunitiesComputer softwareConsumptionCore FacilityCouplingCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDNA mutationDataDevelopmentDiscipline of Nuclear MedicineDoseDysfunctionESKAPEESKAPE pathogensEnsureFormulationFrustrationFunctional disorderGenetic ChangeGenetic DiseasesGenetic defectGenetic mutationHumanImmune responseInfectionInterdisciplinary ResearchInterdisciplinary StudyInvestigatorsKnowledgeLabelLung infectionsLyticMath ModelsMiceMice MammalsMiscellaneous AntibioticModelingModern ManModernizationMucoviscidosisMultidisciplinary CollaborationMultidisciplinary ResearchMurineMusMutationNuclear MedicineP aeruginosaP. aeruginosaPETPET ScanPET imagingPETSCANPETTPK/PDPersonsPhagesPharmaceutical AgentPharmaceuticalsPharmacologic SubstancePharmacological StudyPharmacological SubstancePharmacologyPharmacology StudyPhysiopathologyPlaque AssayPositron Emission Tomography Medical ImagingPositron Emission Tomography ScanPositron-Emission TomographyPre-Clinical ModelPreclinical ModelsProductionProtocolProtocols documentationPseudomonas aeruginosaPseudomonas pyocyaneaRad.-PETRadioactive IsotopesRadioisotopesRadiolabeledRadiology / Radiation Biology / Nuclear MedicineRadionuclidesRatRats MammalsRattusReagentRegimenResearchResearch PersonnelResearchersRespiratory InfectionsRespiratory Tract InfectionsRodentRodentiaRodents MammalsSamplingSightSiteSoftwareStandardizationStudy modelsTechniquesTechnologyTestingTherapeuticTimeTranslatingTranslationsUniversitiesViralVisionWorkanalytical methodanti-microbial resistantanti-microbial resistant infectionantimicrobial resistant infectionbacteria infectionbacterial diseasebacterial virusbusiness-friendly environmentcollaborative atmospherecollaborative environmentcystic fibrosis transmembrane regulatordesigndesigningdevelop therapydevelopmentaldrug developmentempowermentexperimentexperimental researchexperimental studyexperimentsfirst in manfirst-in-humangenetic conditiongenetic disordergenome mutationhost responseimaging approachimaging based approachimmune system responseimmunoresponseinfectious disease modelinnovateinnovationinnovativeinteractive atmosphereinteractive environmentinterdisciplinary atmosphereinterdisciplinary environmentintervention developmentmathematic modelmathematical modelmathematical modelingmodel of animalmultidisciplinaryneutralizing antibodynovelnuclear imagingpathophysiologypeer-group atmospherepeer-group environmentpharmaceuticalpharmacokinetic modelpharmacokinetics and pharmacodynamicspharmacologicpositron emission tomographic (PET) imagingpositron emission tomographic imagingpositron emitting tomographypre-clinical developmentpre-clinical studypreclinical developmentpreclinical studypulmonary infectionsradiolabelingradiologically labeledresistance to anti-microbialresistant to antimicrobialrespiratorytherapy developmenttooltranslationtreatment developmentvisual function
Description preview
PROJECT SUMMARY/ABSTRACT
Bacteriophages (phages) – viral predators of bacteria – are a promising solution to antimicrobial-resistant
bacterial infections caused by ESKAPE pathogens, particularly for Pseudomonas aeruginosa airway infections
in people with cystic fibrosis (CF), a genetic disease involving mutations in the CFTR protein. While phage…
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