grant
Testing sex as a moderator of health impacts of upward mobility on indicators for AD risk in young adulthood
Organization UNIVERSITY OF CALIFORNIA LOS ANGELESLocation LOS ANGELES, UNITED STATESPosted 15 Sept 2024Deadline 31 Aug 2029
NIHUS FederalResearch GrantFY202512-20 years old21+ years oldAD dementiaActive Follow-upAdmissionAdmission activityAdolescenceAdolescentAdolescent YouthAdultAdult HumanAgeAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer risk factorAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimer's disease riskAlzheimers DementiaAmentiaApolipoproteinsBloodBlood - brain barrier anatomyBlood Reticuloendothelial SystemBlood-Brain BarrierBrainBrain Nervous SystemCell Communication and SignalingCell SignalingChildhoodCognitionCognitiveDataDementiaDevelopmentDifferences between sexesDiffers between sexesDysfunctionEducationEducational aspectsEncephalonExhibitsExperimental DesignsFamilyFecesFemaleFollow-Up StudiesFollowup StudiesFunctional disorderGI microbiomeGenderGender RoleGenesGenetic predisposing factorGut Epithelial PermeabilityGut HyperpermeabilityGut permeabilityHealthHealth Care CostsHealth CostsHemato-Encephalic BarrierImpoverishedIndividualInequityInflammationInflammatoryIntestinal Epithelial PermeabilityIntestinal HyperpermeabilityIntestinal permeabilityIntracellular Communication and SignalingLifeLinkMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMeasuresMediatingMediatorMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceNMR ImagingNMR TomographyNatural experimentNeighborhoodsNerve DegenerationNeuron DegenerationNuclear Magnetic Resonance ImagingObesityObservation researchObservation studyObservational StudyObservational researchOutcomePathway interactionsPatient Self-ReportPeripheralPhysiopathologyPovertyPrimary Senile Degenerative DementiaPublic HealthRandomizedReportingRiskRisk FactorsRisk ReductionSchoolsSelf-ReportSex DifferencesSex RolesSexual differencesSignal TransductionSignal Transduction SystemsSignalingStandardizationStressStructureStudentsTestingWomanYouthYouth 10-21Zeugmatographyactive followupadiposityadolescence (12-20)adult youthadulthoodagesalzheimer riskarmbiological signal transductionbloodbrain barrierbrain healthcognitive abilitycognitive functioncohortcorpulencedevelopmentaldigestive tract microbiomeearly adulthoodemerging adultenteric microbiomeexpectationexperimentexperimental researchexperimental studyexperimentsfollow upfollow-upfollowed upfollowupgastrointestinal microbiomegenetic risk factorgut microbiomegut to brain axisgut-associated microbiomegut-brain axisgut-brain communicationgut-brain interactionsgut-brain relationshipgut-brain signalinghigh schoolindexinginflammation markerinflammatory markerinherited factorintestinal biomeintestinal microbiomejuvenilejuvenile humanlater in lifelater lifemalemetagenomemicrobiomenerve injuryneural degenerationneural inflammationneural injuryneurocognitive testneurodegenerationneurodegenerativeneuroinflammationneuroinflammatoryneurological degenerationneuronal degenerationolder adultolder adulthoodpathophysiologypathwaypediatricphysical conditioningphysical healthprimary degenerative dementiarandomisationrandomizationrandomly assignedrecruitreduce riskreduce risksreduce that riskreduce the riskreduce these risksreduces riskreduces the riskreducing riskreducing the riskresilienceresilientretention rateretention strategyrisk-reducingsenile dementia of the Alzheimer typesexsex based differencessex-dependent differencessex-related differencessex-specific differencessocialstoolsystemic inflammationsystemic inflammatory responseyoung adultyoung adult ageyoung adulthoodyouth age♀♂
Description preview
Abstract
Early poverty and lower education attainment are associated with increased rates of Alzheimer's
Disease (AD), and lower cognitive functioning in later adulthood. Upwardly mobile youth who
“strive” to rise above poverty typically have better cognitive outcomes in early adulthood.
However, our preliminary data suggest that striving during…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click