grant
Testing effects of cash transfers on biological aging and risk for Alzheimer's Disease
Organization COLUMBIA UNIVERSITY HEALTH SCIENCESLocation NEW YORK, UNITED STATESPosted 1 May 2024Deadline 28 Feb 2029
NIHUS FederalResearch GrantFY202621+ years oldAD and related dementiaAD dementiaAD related dementiaAD riskAD risk factorADRDAccelerationActivities of Daily LivingActivities of everyday lifeAddressAdultAdult HumanAfricaAfrica South of the SaharaAgeAgingAlgorithmsAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer risk factorAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimer's Disease and its related dementiasAlzheimer's and related dementiasAlzheimer's dementia and related dementiaAlzheimer's dementia or related dementiaAlzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease and related forms of dementiaAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementiaAlzheimer's disease related dementiaAlzheimer's disease riskAlzheimers DementiaAmentiaAssayBioassayBiologicalBiological AgingBiological AssayBloodBlood Reticuloendothelial SystemCell BodyCellsChronic DiseaseChronic IllnessCognitionCognitive agingCommunicable DiseasesConsumptionControl GroupsDNA MethylationDataDementiaDevelopmentDiseaseDisease OutcomeDisorderDrynessEOADEarly Onset Alzheimer DiseaseEconomicsExhibitsGenerationsGovernmentGrimAge clockHannum clockHealthHealth BenefitHorvath clockHouseholdHypertensionImmuneImmunesImmunityIndividualInfectious DiseasesInfectious DisorderInfluentialsInternationalInterventionKnowledgeLifeLinkLong-term Follow-upLongitudinal StudiesLongitudinal SurveysLow-resource areaLow-resource communityLow-resource environmentLow-resource regionLow-resource settingMalawiMeasurementMeasuresMethodsNeurocognitiveNutritionNyasalandObesityOlder PopulationParticipantPatternPhenoAge clocksPhenotypePopulationPrevalencePrimary Senile Degenerative DementiaProtocolProtocols documentationPublic HealthRandomization trialRandomized, Controlled TrialsResearchResearch SpecimenResource-constrained areaResource-constrained communityResource-constrained environmentResource-constrained regionResource-constrained settingResource-limited areaResource-limited communityResource-limited environmentResource-limited regionResource-limited settingResource-poor areaResource-poor communityResource-poor environmentResource-poor regionResource-poor settingRiskRisk FactorsRisk ReductionRoleSamplingSouth AfricaSpecimenSpottingsSub-Saharan AfricaSubsaharan AfricaSurvey InstrumentSurveysTestingTimeUnderweightVascular Hypertensive DiseaseVascular Hypertensive DisorderWaiting Listsaccelerated agingaccelerated biological ageaccelerated biological agingadiposityadult youthadulthoodage accelerationaged groupaged groupsaged individualaged individualsaged peopleaged personaged personsaged populationaged populationsagesaging associatedaging associated diseaseaging associated disordersaging populationaging relatedaging related diseaseaging related disordersalzheimer riskbiologicbiological agebiological process of ageburden of diseaseburden of illnesschronic disordercognitive assessmentcognitive functioncognitive testingcohortcorpulencedaily living functiondaily living functionalitydementia riskdevelopmentaldisease associated with agingdisease burdendisease of agingdisease riskdisorder of agingdisorder riskdisorders associated with agingdisorders related to agingearly adversityearly childhood adversityearly life adversityearly onset ADearly onset Alzheimer'seconomicepigenetic age clocksepigenetic clockepigenetic molecular clocksexperiencefunctional abilityfunctional capacityhealthspanhealthy life spanhigh blood pressurehyperpiesiahyperpiesishypertensive diseasehypertensive disorderimprovedinnovateinnovationinnovativeinsightintervention effectlife spanlifespanlong-term followuplong-term studylongitudinal outcome studieslongitudinal research studymethylation clockmortalityneurocognitive testnovelolder adultolder adulthoodolder groupsolder individualsolder personpace of agingpace of biological agingpathogenpopulation agingpreventpreventingprimary degenerative dementiaprogramsrandomized control trialrandomized trialrate of agingrate of biological agingreduce riskreduce risksreduce that riskreduce the riskreduce these risksreduces riskreduces the riskreducing riskreducing the riskrisk factor for dementiarisk factor for developing Alzheimer'srisk factor in Alzheimer'srisk for dementiarisk of developing Alzheimer'srisk-reducingsenile dementia of the Alzheimer typesocialsocial rolespeed of agingspeed of the agingtooltreatment groupwaitlistyoung adultyoung adult ageyoung adulthood
Description preview
Alzheimer's Disease (AD) and AD-Related Disorders (AD/ADRD) are significantly increasing in
resource-limited areas, where improved nutrition and decreased infectious disease mortality are
enabling population aging. Simultaneously, enduring elevated levels of early-life adversity and
adult hardship accelerates the development of aging-related…
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