grant

Taking Our Shot: Extended-Release Naltrexone as Opioid Overdose Pre-Exposure Prophylaxis (PrEP) in People Using Stimulants Living With or At Risk of HIV

Organization UNIVERSITY OF CALIFORNIA, SAN FRANCISCOLocation SAN FRANCISCO, UNITED STATESPosted 1 Jul 2024Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2024AIDS VirusAIDS preventionAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusActiqAddressBiological MarkersCaliforniaCaringCessation of lifeClinicCocaineCountyCouplesCreativenessCrystal MethCrystal methamphetamineDeathDeath RateDeoxyephedrineDesoxyephedrineDrug userDrugsDuragesicEffectivenessEpidemiologyExposure toFentanestFentanylFentylGeneral HospitalsHIVHIV PreventionHIV/AIDS preventionHarm MinimizationHarm ReductionHealthHomeHuman Immunodeficiency VirusesIndividualInjectableIntramuscularLAV-HTLV-IIILife ExpectancyLinkLymphadenopathy-Associated VirusMedicationMedicineMethamphetamineMethodsMethylamphetamineN-MethylamphetamineNalorexNaltrexoneNemexinOpiate AntagonistOpiate receptor antagonistOpiatesOpioidOpioid AntagonistOpioid receptor antagonistPWUDPatientsPersonsPharmaceutical PreparationsPhentanylPopulationPrEPPreventative measurePreventionPreventive measureRandomizedRandomized, Controlled TrialsReViaResearchRiskSan FranciscoStimulantTestingUnited StatesUniversitiesVirus-HIVVivitrolalcohol use disorderantiretroviral therapyantiretroviral treatmentbio-markersbiologic markerbiomarkercohortcreativitydrug/agentepidemiologicepidemiologicalethanol use disorderexperiencefentanyl exposurehomesinnovateinnovationinnovativeinsightmethmortality ratemortality rationovelopiate consumptionopiate deathsopiate drug useopiate exposureopiate intakeopiate mortalityopiate overdoseopiate related overdoseopiate useopioid consumptionopioid deathsopioid drug overdoseopioid drug useopioid exposureopioid induced overdoseopioid intakeopioid intoxicationopioid medication overdoseopioid mortalityopioid overdoseopioid overdose deathopioid poisoningopioid related deathopioid related overdoseopioid toxicityopioid useoral HIVoverdose deathoverdose fatalitiesoverdose preventionparticipant interviewpeople who use drugspeople who use illicit drugspersons who use drugspre-exposure prophylaxispreventpreventingpsychostimulant userandomisationrandomizationrandomized control trialrandomly assignedstimulant usesubstance usesubstance usingtooluse of stimulantsward
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PROJECT SUMMARY
Cocaine and methamphetamine-related deaths have risen steeply in the United States, the majority associated

with fentanyl. Stimulant use is prevalent among people living with or at risk for HIV, and in this population, it is

unknown what proportion of mixed stimulant-opioid overdose deaths are due to unintentional fentanyl…

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Taking Our Shot: Extended-Release Naltrexone as Opioid Overdose Pre-Exposure Prophylaxis (PrEP) in People Using Stimulan | Dev Procure