grant
Structure, Function and Pharmacology of Neurotransmitter Reuptake Systems
Organization NATIONAL INSTITUTE OF MENTAL HEALTHLocation UNITED STATES
NIHUS FederalResearch GrantFY20250-11 years old3,4 methylenedioxymethamphetamine3-Hydroxy-3-methylglutaryl CoA Reductase5-HT5-HT(1A) Receptor5-HT1A Receptor5-Hydroxytryptamine5-Hydroxytryptamine 1A Receptor5HTAD/HDADHDASDAbscissionAcuteAddressAdenosine Cyclic Monophosphate-Dependent Protein KinasesAffectAgonistAminesAmphetaminesAntipsychotic AgentsAntipsychotic DrugsAntipsychoticsAstrocytesAstrocytusAstrogliaAttention Deficit DisorderAttention deficit hyperactivity disorderAutismAutistic DisorderAutoregulationBasal GangliaBasal NucleiBehavioralBiochemicalBiologicalBiotinCarrier ProteinsCell BodyCell Communication and SignalingCell FunctionCell NucleusCell PhysiologyCell ProcessCell SignalingCell membraneCell surfaceCellsCellular FunctionCellular PhysiologyCellular ProcessChemosensitizationChemosensitization/PotentiationChildChild YouthChildren (0-21)CholesterolCholesterol HomeostasisCocaineCommon Rat StrainsComplexConcertaCrystal MethCrystal methamphetamineCyclic AMP-Dependent Protein KinasesCytoplasmic MembraneD2 receptorDA NeuronDAT dopamine transporterDRD2 ReceptorDaytranaDeoxyephedrineDesoxyephedrineDesoxynorephedrinDiseaseDisorderDopamineDopamine D2 ReceptorDopamine neuronDrug TargetingDrug TherapyDrug usageDrugsEAAT3Early Infantile AutismEnteramineEnzyme GeneEnzymesEventExcisionExtirpationG-ProteinsGTP-Binding ProteinsGTP-Regulatory ProteinsGene ExpressionGene TranscriptionGenesGenetic TranscriptionGlutamate TranslocaseGlutamate Transport GlycoproteinGlutamate TransporterGlutamatesGuanine Nucleotide Coupling ProteinGuanine Nucleotide Regulatory ProteinsHMG CoA ReductasesHippophaineHomeostasisHumanHydroxymethylglutaryl-CoA reductaseHydroxytyramineIncidenceInfantile AutismIntracellular Communication and SignalingKanner's SyndromeL-GlutamateLDL ReceptorsLDLR geneLabelLaboratoriesLearningLevarterenolLevonorepinephrineLigandsLigaseLigase GeneLipoprotein LDL ReceptorsLocomotor ActivityLow Density Lipoprotein ReceptorMDMAMajor Depressive DisorderMajor TranquilizersMajor Tranquilizing AgentsMass Photometry/Spectrum AnalysisMass SpectrometryMass SpectroscopyMass SpectrumMass Spectrum AnalysesMass Spectrum AnalysisMediatingMedicationMembrane Protein GeneMembrane ProteinsMembrane-Associated ProteinsMental disordersMental health disordersMesencephalonMetadateMethamphetamineMethylamphetamineMethylenedioxymethamphetamineMethylphenidateMid-brainMidbrainMidbrain structureModern ManMonomeric G-ProteinsMonomeric GTP-Binding ProteinsMotor ActivityMovementN,alpha-dimethyl-1,3-benzodioxole-5-ethanamineN-Methyl-3,4-methylenedioxyamphetamineN-MethylamphetamineNerve CellsNerve Impulse TransmissionNerve TransmissionNerve Transmitter SubstancesNerve UnitNeural CellNeurocyteNeuroleptic AgentsNeuroleptic DrugsNeurolepticsNeuronal TransmissionNeuronsNeurotransmittersNoradrenalineNorepinephrineNucleusObsessive-Compulsive DisorderObsessive-Compulsive NeurosisPKAPathway interactionsPharmaceutical PreparationsPharmacological TreatmentPharmacologyPharmacotherapyPhasePhase 2 Clinical TrialsPhase II Clinical TrialsPhenaminePhenoprominPhysiologicPhysiologicalPhysiological HomeostasisPlasma MembranePotentiationPredominantly Hyperactive-Impulsive Type Attention-Deficit DisorderPredominantly Hyperactive-Impulsive Type Hyperactivity DisorderProtein Kinase AProtein TraffickingProteinsPsychiatric DiseasePsychiatric DisorderRNA ExpressionRNA SeqRNA analysisRNA sequencingRNAseqRatRats MammalsRattusReceptor ActivationReceptor ProteinRegulationRegulatory PathwayRemovalResearchRibosomesRitalinRoleSchizophreniaSchizophrenic DisordersSerotoninSerotonin 1A ReceptorSerotonin Receptor 5-HT1AShapesSignal PathwaySignal TransductionSignal Transduction SystemsSignalingSmall G-ProteinsSmall GTPasesStructureSubcellular ProcessSubstantia NigraSubstantia nigra structureSurface ProteinsSurgical RemovalSynthetasesSystemTechniquesTherapeuticTranscriptionTransgenic MiceTranslatingTransport Protein GeneTransport ProteinsTransporter ProteinUpregulationVentral Tegmental AreaVitamin HWorkabused drugabused drugsamineastrocytic gliaautism spectral disorderautism spectrum disorderautistic spectrum disorderaxon signalingaxon-glial signalingaxonal signalingbehavior phenotypebehavioral phenotypingbiologicbiological signal transductionbody movementcAMP-Dependent Protein Kinasescell typecholesterol metabolismclinical depressioncoenzyme Rdementia praecoxdl-Amphetaminedopamine transporterdopaminergic neurondrug abuseddrug actiondrug interventiondrug of abusedrug treatmentdrug usedrug/agentdrugs abuseddrugs of abuseecstasyexcitatory amino acid transporter 3experimentexperimental researchexperimental studyexperimentsexposure to methexposure to methamphetamineglia signalingglial signalingglutamatergickidsmajor depressionmajor depression disordermental illnessmethmeth exposuremethamphetamine exposurenerve signalingneural signalingneuronalneuronal signalingneuropsychiatric diseaseneuropsychiatric disorderneurotransmissionneurotransmitter reuptakeneurotransmitter transportnovelpathwaypharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticsphase II protocolplasmalemmapresynapticprotein activationprotein complexprotein transportpsychiatric illnesspsychological disorderreceptorrepetitive behaviorresectionresponseschizophrenicsocial roletraffickingtranscriptome sequencingtranscriptomic sequencingtranscriptomicsventral tegmentumyoungster
Description preview
Drugs which act on neurotransmitter transport systems are among the most widely used treatments for neuropsychiatric disorders, including major depression and attention-deficit disorders. These transporters are also a target for drugs of abuse such as methamphetamine (METH), MDMA (ecstasy) and cocaine. My laboratory has used cell biological,…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click