grant
State-dependent modulation of learning
Organization VIRGINIA COMMONWEALTH UNIVERSITYLocation RICHMOND, UNITED STATESPosted 18 Apr 2024Deadline 31 Mar 2029
NIHUS FederalResearch GrantFY2025Absolute ethanolAddressAlcohol IntoxicationAlcoholic IntoxicationAnimal TestingAnimalsAssociation LearningAssociative LearningAttenuatedBehaviorC elegansC. elegansC.elegansCaenorhabditis elegansCell Communication and SignalingCell SignalingCuesDependenceDevelopmentDopamineDrugsDrunkennessETOHEnvironmentEtOH intoxicationEthanolEthyl AlcoholEventFailureFoodGeneticGoalsGrain AlcoholHistoryHumanHungerHydroxytyramineIntoxicationIntracellular Communication and SignalingInvertebrataInvertebratesLearningLevarterenolLevonorepinephrineMedicationMemoryMethylcarbinolModelingModern ManModificationMolecularMoodsNatureNematodaNematodesNerve CellsNerve Impulse TransmissionNerve TransmissionNerve UnitNervous SystemNeural CellNeurocyteNeurologic Body SystemNeurologic Organ SystemNeuronal TransmissionNeuronsNoradrenalineNorepinephrineNorsympatolNorsynephrineOctopamineOlfactory LearningPathway interactionsPavlovian conditioningPeptide Signal SequencesPeptidesPharmaceutical PreparationsProcessReceptor ProteinRecording of previous eventsShapesSignal PeptideSignal SequencesSignal TransductionSignal Transduction SystemsSignalingSpecificityStarvationSystemTemperatureTestingTrainingWorkanalogassociative conditioningattenuateattenuatesaxon signalingaxon-glial signalingaxonal signalingbiological signal transductionclassical conditioningdevelopmentaldrug/agentethanol intoxicationexperienceforgettingglia signalingglial signalinghistoriesinsightlearned behaviorlearning behaviormemory encodingmemory recallnerve signalingneural circuitneural circuitryneural signalingneurocircuitryneuronalneuronal signalingneurotransmissionnovelpathwayprotein signal sequencereceptorresponseroundwormsocial situationsynaptic circuitsynaptic circuitry
Description preview
PROJECT SUMMARY
Animals can modulate learning in response to differing internal and external environments. Layering context
onto learned information can enhance the diversity and specificity of memories, and can allow efficient access
to situation-specific behaviors. In state-dependent learning (SDL), information learned by an animal while it is…
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