grant
Sodium Glucose Cotransporter-2 Inhibitors for the Amelioration of Acute Cardio-Renal Syndrome
NIHUS FederalResearch GrantFY202621+ years oldAcuteAcute Kidney FailureAcute Kidney InsufficiencyAcute Renal FailureAcute Renal InsufficiencyAdultAdult HumanAdult-Onset Diabetes MellitusAnimal ModelAnimal Models and Related StudiesAwardBiochemicalBiological MarkersBiometricsBiometryBiostatisticsBloodBlood Reticuloendothelial SystemBlood SerumCardiac Failure CongestiveCardiorenal diseaseCardiorenal dysfunctionCardiorenal syndromeCardiovascular DiseasesClinicalClinical ResearchClinical StudyClinical TrialsClinical Trials DesignCohort StudiesCongestive Heart FailureCreatinineD-GlucoseDextroseDiabetes MellitusDiabetic AcidosisDiabetic KetoacidosisDiabetic KetosisDisease ProgressionDistressDiuresisDiureticsDrugsElectrolytesEligibilityEligibility DeterminationEndotheliumEnvironmentEventFutureGU InfectionGenitourinary System InfectionGenitourinary infectionGlucoseGoalsHealthHeart DecompensationHeart failureHospital AdmissionHospital CostsHospitalizationHospitalization costHospitalsHumanHypoglycemiaHypoglycemic AgentsHypoglycemic DrugsHypoglycemicsHypotensionIncidenceIndividualInflammationInjuryInjury to KidneyInpatientsInterruptionInvestigatorsKetosis-Resistant Diabetes MellitusKidneyKidney DiseasesKidney Urinary SystemLength of StayLow Blood PressureMaturity-Onset Diabetes MellitusMedicationMedicineMentorshipModern ManMonitorMorbidityNIDDMNa elementNephrologyNephropathyNon-Insulin Dependent DiabetesNon-Insulin-Dependent Diabetes MellitusNoninsulin Dependent DiabetesNoninsulin Dependent Diabetes MellitusNumber of Days in HospitalOralOutcomeOxidative StressParticipantPatient CarePatient Care DeliveryPatientsPharmaceutical EpidemiologyPharmaceutical PreparationsPharmacoepidemiologyPhysiologyPlacebosPopulationProtocol ScreeningProviderProximal Kidney TubulesRandomizedRecoveryRenal DiseaseRenal functionReportingResearchResearch PersonnelResearchersResistanceRetrospective cohortSGLT 2 inhibitorSGLT2iSafetySamplingSerumSham TreatmentSlow-Onset Diabetes MellitusSodiumSodium glucose co-transporter 2 inhibitorStable Diabetes MellitusSyndromeT2 DMT2DT2DMTestingTherapeuticTrainingTranslational ResearchTranslational ScienceTreatment FailureTubularTubular formationType 2 Diabetes MellitusType 2 diabetesType II Diabetes MellitusType II diabetesUrineVascular Hypotensive DisorderVenousabsorptionacute kidney injuryadult onset diabetesadulthoodantihyperglycemicbio-markersbiobankbiologic markerbiomarkerbiomarker selectionbiorepositorycardiac failurecardiovascular disordercardiovascular riskcardiovascular risk factorcare for patientscare of patientscaring for patientschronic heart failurecohort research studycohort surveydecline in functiondecline in functional statusdetermine efficacydiabetesdiabetes mellitus therapydiabetes therapydiabeticdiabetic ketoacidoticdrug epidemiologydrug/agentearly biomarkersearly detection biomarkersearly detection markersefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationenergy efficiencyevaluate efficacyexamine efficacyfunctional declinefunctional status declinehospital dayshospital length of stayhospital stayhypoglycemichypoglycemic episodesimprovedinfectious disease of genitourinary systeminjuriesinstructorketosis resistant diabeteskidney disorderkidney dysfunctionkidney functionkidney injurymaturity onset diabetesmeetingmeetingsmodel of animalmortalitynon-diabeticnondiabeticpharmacoepidemiologicpharmacoepidemiologicalpre-clinicalpreclinicalprimary end pointprimary endpointprognosticrandomisationrandomizationrandomized placebo control trialrandomized placebo controlled trialrandomized placebo-controlled clinical trialrandomized, clinical trialsrandomly assignedrenalrenal disorderrenal dysfunctionrenal injuryrenal proximal tubulerepairrepairedresistantresponsesafety assessmentsecondary outcomesham therapyside effecttherapy failuretraditional therapytranslation researchtranslational investigationtype 2 DMtype II DMtype two diabetesurogenital infection
Description preview
PROJECT SUMMARY | Candidate: The candidate is an Instructor of Medicine (Nephrology) with 3 years of
ongoing training in clinical research in acute kidney injury (AKI) and clinical trial design and conduct under the
mentorship of the director of Yale’s Clinical and Translational Research Accelerator, a leading expert in clinical
trials and…
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