grant
Skeletal Muscle Remodeling and Intramuscular Adipose Tissue following Traumatic Knee Injury
Organization UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAHLocation SALT LAKE CITY, UNITED STATESPosted 20 Jul 2024Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY202521+ years oldACL injuryACL reconstructionACL repairAcuteAdipocytesAdipose CellAdipose tissueAdultAdult HumanAgeAgingAreaAthleticBiologicalBiologyBiometricsBiometryBiopsyBiostatisticsBody TissuesCartilageCartilaginous TissueCausalityChronicClinicalClinical TrialsConduct Clinical TrialsDataDegenerative ArthritisDegenerative polyarthritisDevelopmentDiagnosisDietDiseaseDisorderEarly DiagnosisEtiologyExtensorFacultyFat CellsFatty TissueFibrosisFundingGeneralized GrowthGoalsGrowthHealthImpairmentIndividualInfiltrationInflammatoryInjuryInterventionIntramuscularInvestigationInvestigatorsK01 AwardK01 MechanismK01 ProgramKneeKnee InjuriesKnowledgeLeadershipLinear RegressionsLipidsLipocytesMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMature LipocyteMature fat cellMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMedical RehabilitationMedicineMentored Research Scientist Development AwardMentored Training AwardMentorsMentorshipModelingMolecularMuscleMuscle AtrophyMuscle DevelopmentMuscle TissueMuscle WeaknessMuscle functionMuscular AtrophyMuscular DevelopmentMuscular WeaknessMusculoskeletalNIAMSNMR ImagingNMR TomographyNational Institute of Arthritis, and Musculoskeletal, and Skin DiseasesNational Institutes of HealthNeurologistNuclear Magnetic Resonance ImagingObesityOperative ProceduresOperative Surgical ProceduresOrthopedic SurgeryOsteoarthritisOsteoarthrosisOutcomePatientsPhysiatric ProcedurePhysical Medicine ProcedurePhysical RehabilitationPhysical TherapeuticsPhysical activityPhysical therapyPhysiologicPhysiologicalPhysiotherapyPopulationPropertyRecoveryRehabilitationRehabilitation OutcomeRehabilitation therapyResearchResearch PersonnelResearch PriorityResearch Scientist Development AwardResearchersRiskRisk FactorsSkeletal MuscleSourceSports MedicineStrategic PlanningSurgicalSurgical InterventionsSurgical ProcedureTechniquesTestingTimeTissue GrowthTissuesTorqueTrainingTraumatic ArthritisTraumatic ArthropathyTraumatic injuryTreatment CostUnited States National Institutes of HealthUniversitiesUtahVoluntary MuscleWorkZeugmatographyadiposeadiposityadult youthadulthoodage associated alterationsage associated changesage associated differenceage associated effectsage associated muscle atrophyage based differenceage correlated alterationsage correlated changesage dependent alterationsage dependent changesage dependent differenceage dependent variationage differenceage effectage induced alterationsage induced changesage related alterationsage related changesage related differenceage related effectsage related pathwaysage related variationage specific alterationsage specific changesage specific differenceage-associated decline in muscleage-associated muscle declineage-associated muscle deteriorationage-associated muscle lossage-associated muscle wastingage-related decline in muscleage-related muscle declineage-related muscle deteriorationage-related muscle lossage-related muscle wastingagedagesaging associated alterationsaging associated changesaging associated mechanismaging correlated alterationsaging correlated changesaging dependent alterationsaging dependent changesaging effectaging induced alterationsaging induced changesaging mechanismaging pathwayaging related alterationsaging related changesaging related mechanismaging related pathwaysaging specific alterationsaging specific changesalterations with ageanterior cruciate ligament injuryanterior cruciate ligament reconstructionanterior cruciate ligament repairbasebasesbiologicbiological mechanism of agebiological pathways of agecareercareer developmentcartilage degenerationcartilage degradationcausationcell typechanges with ageclinical decision-makingclinical imagingcohortcollegecollegiatecorpulencecytokinedecreased muscle strengthdegenerative joint diseasedesigndesigningdevelopmentaldietsdiffer by agedifference across agedifference in agedisease causationdynapeniaearly detectionexperienceextremity injuryextremity traumahypertrophic arthritisimpact of ageimprovedinfluence of ageinjuriesinjury to extremityjoint damagejoint injuryjoint traumalife spanlifespanlimb injurylimb traumalow muscle strengthmechanism regulating agingmechanisms involved in agingmembermid lifemid-lifemiddle agemiddle agedmidlifemuscle breakdownmuscle degradationmuscle deteriorationmuscle lossmuscle strengthmuscle strength declinemuscle strengtheningmuscle wastingmuscularontogenypathway involved in agingpatient barrierspatient-level barrierspersonalized health carephysical rehabpost-operative rehabpost-operative rehabilitationpost-traumatic osteoarthritispostoperative rehabpostoperative rehabilitationprecision health carepreventpreventingprimary outcomeprofessorprogenitorprogenitor cell functionprogenitor functionquadricepsquadriceps musclerecruitreduced muscle strengthrehab therapyrehabilitativerehabilitative outcomerehabilitative therapyrotator cuff injurysarcopeniasarcopenicsexskeletal muscle atrophyskeletal muscle breakdownskeletal muscle lossskeletal muscle protein lossskeletal muscle wastingskeletal muscle weaknessskillsstem and progenitor cell functionstem and progenitor functionstem cell functionstrength trainingsurgerytranslational investigatortranslational researchertranslational scientistvariation by agevastus lateraliswhite adipose tissueyellow adipose tissueyoung adultyoung adult ageyoung adulthoodyounger age
Description preview
PROJECT ABSTRACT
This is an application for the NIAMS K01 Mentored Research Scientist Development award for Dr. Stephan
Bodkin, an Assistant Professor in the Department of Physical Therapy and Athletic Training in the College of
Health at the University of Utah. Dr. Bodkin is establishing himself as an emerging leader in sports medicine
research,…
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