grant
Shared Resources Core-Viral Vector Core
Organization UNIVERSITY OF WASHINGTONLocation SEATTLE, UNITED STATESPosted 7 May 2014Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY2025AAV vectorAAV-based vectorAnimal ModelAnimal Models and Related StudiesAnimalsAntibodiesAntiseraBasic ResearchBasic ScienceBiotechBiotechnologyCK8CMVCanine SpeciesCanis familiarisCapsidCardiac Muscle CellsCardiac MyocytesCardiocyteCell BodyCell LineCellLineCellsCentrifugationCentrifugation FractionationChargeClinical ResearchClinical StudyCollaborationsComplementary DNAConsumptionCytokeratin-8 Staining MethodCytomegalovirusDNA TherapyDoctor of PhilosophyDogsDogs MammalsDystrophinDystrophin-Related ProteinDystrophin-Related Protein 1Embryonic Muscle CellsFamily suidaeFundingGene DeliveryGene TransferGene Transfer ClinicalGenesGenetic InterventionHCMVHPLCHandHeart Muscle CellsHeart myocyteHigh Performance Liquid ChromatographyHigh Pressure Liquid ChromatographyHigh Speed Liquid ChromatographyHuman ResourcesImmune SeraInvestigatorsIsoformsLaboratoriesLearningLentiviral VectorLentivirus VectorManpowerMedicalMethodsMuscleMuscle DiseaseMuscle DisordersMuscle TissueMuscular DiseasesMuscular DystrophiesMyoblastsMyodystrophicaMyodystrophyMyopathic ConditionsMyopathic Diseases and SyndromesMyopathic disease or syndromeMyopathyPh.D.PhDPigsPlasmid Cloning VectorPlasmid VectorPlasmidsPlayPrecursor Muscle CellsPreparationProceduresProductionProgenitor CellsProtein IsoformsProtocolProtocols documentationQuality ControlRNAi vectorReagentRecombinantsResearchResearch PersonnelResearch ResourcesResearchersResource SharingResourcesRetroviral VectorRetrovirus VectorRoleRoller BottleSalivary Gland VirusesSerotypingServicesSpinal ColumnSpineStrains Cell LinesSuidaeSwineTechniquesTechnologyTimeTrainingTranslational ResearchTranslational ScienceUTRN ProteinUniversitiesUtrophinVertebral columnViralViral VectorVisitWashingtonWorkadeno-associated viral vectoradeno-associated virus vectorbackbonecDNAcaninecardiomyocytecostcultured cell linecytomegalovirus groupdesigndesigningdomestic doggene repair therapygene therapygene-based therapygenetic therapygenomic therapyhandsiPSiPSCiPSCsimmune serumimprovedinduced pluripotent cellinduced pluripotent stem cellinducible pluripotent cellinducible pluripotent stem cellinterestmembermodel of animalmouse modelmurine modelmuscle dystrophymuscularmuscular disorderpersonnelporcinepreparationspreventpreventingresearch studysocial rolestem cellssuidtranslation researchtranslational investigationvectorweb sitewebsite
Description preview
Project Summary – Resource (Vector) Core
The Viral Vector Core was established in 2003 to meet the emerging interest in using AAV & lentiviral vectors
for muscle gene transfer. The required specialized techniques and reagents prevented most labs from being
able to generate the high titer and enormous quantities of vectors needed for systemic gene…
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