grant
Sex differences in circadian output signaling
Organization RUTGERS, THE STATE UNIV OF N.J.Location PISCATAWAY, UNITED STATESPosted 5 Jul 2024Deadline 30 Apr 2029
NIHUS FederalResearch GrantFY2026Abnormal Assessment of MetabolismAgeAgingAnimalsArchitectureBehaviorBehavioralBehavioral GeneticsBiologyBody SystemBody TissuesBrainBrain Nervous SystemCRISPRCRISPR/Cas systemCell Communication and SignalingCell CountCell NumberCell SignalingChronobiologyCircadian RhythmsClustered Regularly Interspaced Short Palindromic RepeatsCommunicationDataDiet rich in fats and sugarsDifferences between sexesDiffers between sexesDrosophila melanogasterEncephalonEngineering / ArchitectureExposure toFliesGene ExpressionGene TranscriptionGeneticGenetic Determinants of BehaviorGenetic ModelsGenetic TranscriptionGoalsHealthHigh Fat DietHumanHumulin RInsulinIntracellular Communication and SignalingKnock-outKnockoutKnowledgeLifeMapsMetabolicMetabolic StudiesMetabolism StudiesModern ManMolecularMorphologyNerve CellsNerve UnitNeural CellNeurocyteNeuronsNeuropeptidesNovolin RNutritionalNyctohemeral RhythmOrgan SystemOrganismOutputPartner in relationshipPeripheralPhylogenyPhysiologyProcessPublishingRNA ExpressionReceptor ProteinRegular InsulinRoleSeasonsSex DifferencesSexual differencesSignal TransductionSignal Transduction SystemsSignalingSignaling MoleculeStressSystemTechniquesTimeTissuesTranscriptionTwenty-Four Hour Rhythmagesbehavior geneticsbehavior studybehavioral studybiological signal transductioncircadiancircadian biologycircadian clockcircadian pacemakercircadian processcircadian rhythmicitycomparing females and malescomparing women and mendaily biorhythmdiet high in fat and sugardietaryfemales compared to malesfemales compared with malesfemales versus malesfemales vs. malesflyhigh-fat/sugar dietimaging approachimaging based approachimprovedin silicoin vivoinsightinsulin signalinglife spanlifespanliving systemluminescencemalematemetabolic abnormality assessmentneuronalnovelnutritiousprogramsreceptorresponsescreeningscreeningssexsex based differencessex dimorphismsex-dependent differencessex-related differencessex-specific differencessexual dimorphismsexually dimorphicsocial rolestressorwomen compared to menwomen compared with menwomen versus menwomen vs. men♂
Description preview
PROJECT SUMMARY/ABSTRACT
Circadian rhythms are the backing track to the symphony of life. Circadian rhythms not only allow organisms to
coordinate their behavior and physiology with daily and seasonal changes but also temporally coordinate
internal processes across organ systems. However, genetic, molecular, circuit, metabolic, and behavioral…
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