grant
Senior Research Career Scientist
Organization LOUIS STOKES CLEVELAND VA MEDICAL CENTERLocation CLEVELAND, UNITED STATESPosted 1 Jan 2019Deadline 31 Dec 2030
VANIHUS FederalResearch GrantFY2026Activities of Daily LivingActivities of everyday lifeAffectAmericanAmputeesAmyotrophic Lateral SclerosisAmyotrophic Lateral Sclerosis Motor Neuron DiseaseAnimal ModelAnimal Models and Related StudiesAnti-InflammatoriesAnti-Inflammatory AgentsAnti-inflammatoryAntioxidantsApoplexyAreaArmed Forces PersonnelArtificial ExtremitiesArtificial LimbsAssistive TechnologyAttenuatedBBB crossingBasic ResearchBasic ScienceBathingBathsBehaviorBeliefBiocompatible MaterialsBiologicalBiomaterialsBlood CirculationBloodstreamBody TissuesBrainBrain Nervous SystemBrain Vascular AccidentCNS Nervous SystemCare GiversCaregiversCell BodyCell Communication and SignalingCell SignalingCellsCellular immunotherapyCentral Nervous SystemCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCervicalCervical InjuryCervical spinal cord injuryChemistryChronicClinicalClinical TreatmentComputersCorrosivesDNA TherapyDedicationsDeep Brain StimulationDevicesDisablingDiseaseDisorderDrugsElectrodesEncephalonEngineeringEnzyme GeneEnzymesFailureFecesGI microbiomeGehrig's DiseaseGene Transfer ClinicalGenesGenetic InterventionGeometryGoalsGovernmentHealth CareImmunityImplantIndividualInfiltrationInflammatoryInflammatory InfiltrateInflammatory ResponseInjuryInnate Immune SystemInnate ImmunityInstitutionIntracellular Communication and SignalingInvestigationInvestigatorsJournalsLaboratoriesLength of LifeLife ExpectancyLimb ProsthesisLiquid substanceLiteratureLongevityLou Gehrig DiseaseLower ExtremityLower LimbMagazineManuscriptsMechanicsMediatingMedical RehabilitationMedicationMembrum inferiusMembrum superiusMethodsMicroelectrodesMilitaryMilitary PersonnelMiniaturized ElectrodesMissionModelingModulusMolecularMotionMovementMuscleMuscle TissueNamesNanotechnologyNative ImmunityNatural ImmunityNatureNerve CellsNerve DegenerationNerve Impulse TransmissionNerve TransmissionNerve UnitNervous System DiseasesNervous System DisorderNeural CellNeuraxisNeurocyteNeurologic DisordersNeurological DisordersNeuron DegenerationNeuronal TransmissionNeuronsNeurosciencesNon-Specific ImmunityNonspecific ImmunityOutcomeOxidative StressPalsyParalysedPathologicPathway interactionsPatientsPeer ReviewPerformancePersonsPharmaceutical PreparationsPlegiaPolymersPreclinical dataPrivatizationProcessProteinsPublishingQOLQuadriplegiaQuadriplegicQuality of lifeRecoveryRehabilitationRehabilitation therapyReportingResearchResearch PersonnelResearchersResolutionRibosomal RNARoboticsRoleSCI PatientsScienceScientistSelf-Help DevicesSeminalServicesShuntShunt DeviceSignal TransductionSignal Transduction SystemsSignalingSpecificitySpinal Cord TraumaSpinal TraumaSpinal cord injuredSpinal cord injurySpinal cord injury patientsSterilityStrokeSystemTechnologyTetraplegiaTherapeuticThinkingTimeTissuesTranslatingTraumatic MyelopathyUpper ExtremityUpper LimbVentricularVeteransWorkarmassisted deviceassistive deviceattenuateattenuatesaxon signalingaxon-glial signalingaxonal signalingbiologicbiological materialbiological signal transductionbiomacromolecularbiomacromoleculebiomedical implantblood-brain barrier crossingbloodbrain barrier crossingbody movementbrain attackbrain computer interfacebrain healthbrain machine interfacebrain tissuecareercell-based immunotherapycerebral vascular accidentcerebrovascular accidentclinical applicabilityclinical applicationclinical interventionclinical therapycommunication devicedaily living functiondaily living functionalitydigestive tract microbiomedisabilitydisableddrug/agententeric microbiomeepilepsy monitoringepilepsy recordingepilepsy trackingepileptic monitoringepileptic recordingepileptiform monitoringepileptiform recordingepileptiform trackingepileptogenic monitoringexperiencefallsfeedingfluidfunctional abilityfunctional capacitygastrointestinal microbiomegene repair therapygene therapygene-based therapygenetic therapygenomic therapyglia signalingglial signalinggut microbiomegut-associated microbiomeimmune cell therapyimplant deviceimplantable deviceimplantationimprovedindexingindwelling deviceinjuredinjuriesinterestintestinal biomeintestinal microbiomelimb lossliquidlost limbmaterials sciencemechanicmechanicalmechanical devicemetallicitymicrobiomemilitary populationmimeticsmodel of animalmultidisciplinarymuscularnamenamednamingnano technano technologynano-technologicalnanotechnanotechnologicalnerve signalingneuralneural degenerationneural inflammationneural signalingneurodegenerationneurodegenerativeneuroinflammationneuroinflammatoryneurological degenerationneurological diseaseneuronalneuronal degenerationneuronal signalingneuroprotectionneuroprotectiveneurotransmissionparalysisparalyticpathwaypolymerpolymericpreclinical findingspreclinical informationprosthetic limbrRNArehab therapyrehabilitativerehabilitative therapyresolutionsresponseseizure detectionseizure monitoringseizure recordingseizure trackingshuntssocial rolespatial and temporalspatial temporalspatiotemporalsterilestoolstrokedstrokestetraplegicthoughtstrial regimentrial treatment
Description preview
Overall goals: My laboratory strives to understand and facilitate the neuroinflammatory response to all implanted
devices within the central nervous system. Such devices range from ventricular shunts to various types of
stimulating and recording electrodes. However, most of my efforts have been on intracortical microelectrodes
due to their…
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