grant
SCH: Smart Breath- based Diagnosis of Pulmonary Exacerbations in Children with Cystic Fibrosis through Machine Learning: Towards Noninvasive Health Monitoring in Real-Time
Organization INDIANA UNIVERSITY INDIANAPOLISLocation INDIANAPOLIS, UNITED STATESPosted 9 Sept 2024Deadline 31 May 2028
NIHUS FederalResearch GrantFY20250-11 years oldAI systemAddressAffectAndroid AppAndroid ApplicationAntibiotic AgentsAntibiotic DrugsAntibioticsArtificial IntelligenceBasic ResearchBasic ScienceBiological MarkersBiometricsBiometryBiostatisticsBiotechBiotechnologyBluetoothBody Weight decreasedBreath TestsCF PreschoolersCF lung diseaseCF patientsCardiac DiseasesCardiac DisordersCare GiversCaregiversCell PhoneCell Phone ApplicationCell phone AppCellular PhoneCellular Phone AppCellular Phone ApplicationCellular TelephoneChemistryChildChild YouthChildren (0-21)Children with CFClinicClinicalClinical EvaluationClinical TestingCollaborationsCommunicationComputer ReasoningCoughingCystic FibrosisDataData CollectionDetectionDevelopmentDevicesDiagnosisDisciplineEngineeringEnsureEquipmentExhalationExhalingFamilyGC MSGCMSGas-Liquid-Mass Spectrometry ChromatographyGenetic DiseasesGoalsHealthHealth Care CostsHealth CostsHealth InformaticsHeart DiseasesHomeInstructionInterdisciplinary ResearchInterdisciplinary StudyIntravenousKnowledgeLaboratoriesLife ExpectancyLung DiseasesMachine IntelligenceMachine LearningMass FragmentographiesMass FragmentographyMass-Gas Chromatography SpectrometryMass-Gas Chromatography Spectrum AnalysisMedicalMedicineMetabolic PathwayMiscellaneous AntibioticMissionMobile PhonesMonitorMucoviscidosisMultidisciplinary CollaborationMultidisciplinary ResearchNHLBINational Heart, Lung, and Blood InstituteOutcomePatientsPersonsProductionPublic HealthPublic Health InformaticsPublishingPulmonary Cystic FibrosisPulmonary DiseasesPulmonary DisorderQOLQualifyingQuality of lifeRecoveryResearchResearch ActivityResearch ResourcesResearch SupportResolutionResourcesRespiratory ExpirationSamplingSeveritiesSmart Phone AppSmart Phone ApplicationSmartphone AppSputumStatistical Data AnalysesStatistical Data AnalysisStatistical Data InterpretationSymptomsSystemTechnologyTestingTimeTranslatingTransmissionUnited StatesWeight LossWeight Reductionaccurate diagnosisapp on a smartphoneapplication on a smartphonebio-markersbiologic markerbiomarkerbiomarker arraybiomarker identificationbiomarker panelbiosignaturebody weight lossbreath analysiscandidate biomarkercandidate markercell phone based appchildren with cystic fibrosisclinical testcomputational resourcescomputing resourcesconsumer informaticscostcystic fibrosis lungcystic fibrosis lung diseasecystic fibrosis patientscystic fibrosis preschoolersdesigndesigningdevelopmentaldiagnostic developmentdisease of the lungdisorder of the lungexperiencefrontiergenetic conditiongenetic disorderheart disorderhome testhome-based testhomesiOS appiOS applicationiPhoneiPhone AppiPhone Applicationidentification of biomarkersidentification of new biomarkersimprovedindividuals with CFindividuals with cystic fibrosisinterestion trap mass spectrometrykidslung disorderlung functionmachine based learningmachine learned algorithmmachine learning algorithmmachine learning based algorithmmarker identificationmarker panelmass fragmentometrymobile phone appnano-sized sensorsnanosensingnanosensorsnew markernon-invasive monitornon-invasive systemnoninvasive monitornoninvasive systemnovel biomarkernovel markerover-treatmentovertreatmentpatients with CFpatients with cystic fibrosispediatric cystic fibrosisphone appphone applicationpoint of careprototypepublic health relevancepulmonarypulmonary functionremote diagnosisresearch clinical testingresolutionsresponse to therapyresponse to treatmentsensorsmart devicesmart phonesmartphonesmartphone applicationsmartphone based appsmartphone based applicationstatistical analysistherapeutic responsetherapy responsetransmission processtreatment responsetreatment responsivenessuser-friendlyvolatile organic chemicalvolatile organic compoundwireless communicationwt-lossyoungster
Description preview
Cystic fibrosis (CF) is a genetic disorder that negatively affects young people across the globe. Pulmonary
exacerbations (PEx), episodes of decreased lung function accompanied by coughing, increased sputum
production, and weight loss, are a hallmark of CF lung disease. Besides negative health impacts, PEx
comes with a burden to healthcare…
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