RUI: Exploring the Utility of Antiparallel Triplex-forming CNA Dimers as Sequence-specific DNA Major Groove Binding Agents
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With this award, the Chemistry of Life Processes Program in the Chemistry Division is funding Dr. Thomas Minehan from California State University, Northridge to design and synthesize hybrid molecules that can recognize DNA sequences. Nucleic acid-like bases are attached to a protein-like (carbamate) polymer to create carbamate nucleic acid (CNA)…
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