grant
Role of glucose transport in Alzheimer's disease pathogenesis
Organization UNIV OF ARKANSAS FOR MED SCISLocation LITTLE ROCK, UNITED STATESPosted 15 Apr 2023Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY2025AD dementiaAD modelAPOEAPOE e4APOE-ε4APOEε4Alzheimer Type DementiaAlzheimer beta-ProteinAlzheimer disease dementiaAlzheimer risk factorAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's Amyloid beta-ProteinAlzheimer's DiseaseAlzheimer's amyloidAlzheimer's brainAlzheimer's disease brainAlzheimer's disease modelAlzheimer's disease riskAlzheimers DementiaAmyloid Alzheimer's Dementia Amyloid ProteinAmyloid Beta-PeptideAmyloid Protein A4Amyloid beta-ProteinAmyloid βAmyloid β-PeptideAmyloid β-ProteinApo-EApoE proteinApolipoprotein EAppetiteAstrocytesAstrocytusAstrogliaAβBlood CirculationBloodstreamBrainBrain Nervous SystemChemicalsCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive function abnormalD-GlucoseDNADefectDeoxyribonucleic AcidDesire for foodDeteriorationDextroseDisturbance in cognitionDropsElementsEncephalonEventExhibitsGene Action RegulationGene Expression RegulationGene ModifiedGene RegulationGene Regulation ProcessGene variantGenesGlucoseGlucose Binding ProteinGlucose Transport ProteinGlucose TransporterHumanHyperglycemiaImpaired cognitionInflammationInsulin ResistanceMemoryMiceMice MammalsModern ManMurineMusNerve CellsNerve UnitNeural CellNeurocyteNeurologicNeurologicalNeuronsObesityPancreasPancreaticPathogenesisPerformancePeripheralPhysical activityPlayPrimary Senile Degenerative DementiaPsyche structureRegulatory ElementResearch ResourcesResourcesRoleTestingTherapeutic AgentsTherapeutic Interventiona beta peptideabetaadiposityaged brainaging brainallelic variantalzheimer modelalzheimer riskamyloid betaamyloid-b proteinapo E-4apo E4apo epsilon4apoE epsilon 4apoE-4apoE4apolipoprotein E epsilon 4apolipoprotein E-4apolipoprotein E4astrocytic gliabeta amyloid fibrilbrain tissuecell typecognitive dysfunctioncognitive losscorpulencedrug discoverygene modificationgenetic variantgenetically modifiedgenomic variantglucose transporthyperglycemicinnovateinnovationinnovativeinsulin resistantinsulin toleranceintervention therapymentalmouse modelmurine modelneuronalnovelpharmacologicprimary degenerative dementiasenile dementia of the Alzheimer typesocial rolesoluble amyloid precursor proteinspatial memory
Description preview
Alzheimer’s disease (AD) is associated with a decline in the brain’s use of glucose, its most important fuel. Astrocytes play a key role in shuttling glucose from the bloodstream to where it is needed by the neuronal units of activity deeper in the brain tissue. We find evidence of a defect in a key glucose transport molecule of astrocytes in AD…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click