grant
Rio Grande Valley Cancer Health Disparity Research Center
Organization UNIVERSITY OF TEXAS RIO GRANDE VALLEYLocation EDINBURG, UNITED STATESPosted 18 Aug 2024Deadline 31 Mar 2029
NIHUS FederalResearch GrantFY2026Adrenal GlandsAdrenalsAeroseb-HCAffectAflatoxinsAlcohol DrinkingAlcohol consumptionArbitratingArbitrationB cell differentiation factorB cell stimulating factor 2B-Cell Differentiation FactorB-Cell Differentiation Factor-2B-Cell Stimulatory Factor-2BAY 54-9085BCDFBSF-2BSF2BehavioralBiochemicalBiological Specimen BanksBiological Substance BanksBlood SerumBody TissuesCancer CauseCancer EtiologyCancersCaucasianCaucasian RaceCaucasiansCaucasoidCaucasoid RaceCausalityCell BodyCell Communication and SignalingCell LineCell SignalingCellLineCellsCessation of lifeCetacortChemoresistanceClinicalClinical Treatment MoabCommunicable DiseasesCort-DomeCortefCortenemaCortisolCortisprayCortrilDNA MethylationDataDeathDecrease disparityDermacortDevelopmentDiabetes MellitusDiagnosisDiseaseDisease ProgressionDisorderDisparitiesDisparityDrug resistanceDrugsEldecortEndocrineEtOH drinkingEtOH useEthnic OriginEthnicityEtiologyEventGene variantGenomicsHPGFHealth Disparities ResearchHealth disparities related researchHepatic CancerHepatic DisorderHepatitisHepatocarcinomaHepatocellular CarcinomaHepatocellular cancerHepatocyte-Stimulating FactorHepatomaHeterograftHeterologous TransplantationHispanicHispanic PopulationsHispanic groupHispanic individualHispanic peopleHispanicsHybridoma Growth FactorHydrocortisoneHydrocortoneHypophysisHypophysis CerebriHypothalamic structureHypothalamusHytoneIFN-beta 2IFNB2IL-6IL6 ProteinImmunoblottingIn VitroIncidenceInfectionInfectious DiseasesInfectious DisorderInterleukin-6Intracellular Communication and SignalingLatinoLatino PopulationLatino groupLatino individualLatino peopleLatinosLeptinLiverLiver Cells CarcinomaLiver diseasesLower disparityMEKsMGI-2Malignant NeoplasmsMalignant TumorMalignant neoplasm of liverMeasuresMedicationMetabolic DiseasesMetabolic DisorderMetastasisMetastasizeMetastatic LesionMetastatic MassMetastatic NeoplasmMetastatic TumorMiceMice MammalsModelingMolecularMonoclonal AntibodiesMucinsMucus GlycoproteinMurineMusMyeloid Differentiation-Inducing ProteinNeoplasm MetastasisNutracortOb Gene ProductOb ProteinObese Gene ProductObese ProteinObesityOccidentalOncogenicOrganoidsPDX modelPathway interactionsPatient derived xenograftPatientsPatternPharmaceutical PreparationsPhenotypePhosphorylationPituitaryPituitary GlandPituitary Nervous SystemPlasmacytoma Growth FactorPopulationPositionPositioning AttributePrevalencePrimary carcinoma of the liver cellsProctocortProtein PhosphorylationProteinsR-Series Research ProjectsR01 MechanismR01 ProgramReagentRecurrent diseaseRelapsed DiseaseResearchResearch GrantsResearch Project GrantsResearch ProjectsResearch ResourcesResourcesRisk FactorsRoleSamplingSecondary NeoplasmSecondary TumorSerumSignal TransductionSignal Transduction SystemsSignalingSmokingSmoking BehaviorSocial BehaviorSorafenibStrains Cell LinesStressThesaurismosisTimeTissue SampleTissuesTreatment outcomeValidationWestern BlottingWestern ImmunoblottingXenograftXenograft ModelXenograft procedureXenotransplantationadiposityalcohol ingestionalcohol intakealcohol product usealcohol usealcoholic beverage consumptionalcoholic drink intakeallelic variantbiological signal transductionbiological specimen repositorybiosample repositorybiospecimen bankbiospecimen repositorycancer disparitycancer health disparitycancer metastasiscancer-related health disparitycausationchemoresistantchemotherapychemotherapy resistancechemotherapy resistantcohortcorpulencecultured cell linecytokinedepositorydevelopmentaldiabetesdisease causationdisparity in cancerdisparity in healthdisparity reductiondrinking behaviordrug resistantdrug/agentepigenomeethanol consumptionethanol drinkingethanol ingestionethanol intakeethanol product useethanol useethnic differenceethnicity differencegenetic variantgenomic varianthealth disparities sciencehealth disparityhepatic body systemhepatic diseasehepatic organ systemhepatopathyhistone modificationhypothalamicinnovateinnovationinnovativeinterferon beta 2liver cancerliver carcinomaliver disorderliver malignancymAbsmalignancymalignant liver tumormetabolism disordermitigate disparitymonoclonal Absmortalityneoplasm/cancernoveloverexpressoverexpressionpathwaypatient derived xenograft modelpatient populationpatient prognosisphospho-proteomicsphosphoproteomicsprogramsprotein blottingreduce disparityreduction in disparityrepositoryresistance to Drugresistant to Drugresponsesocial rolesociobehaviorsociobehavioralspecimen bankspecimen repositorystressorsuprarenal glandtumor cell metastasistumorigenicvalidationswhite racexeno-transplantxeno-transplantationxenograft transplant modelxenotransplant model
Description preview
Research Project # 2
Project Summary: Liver cancer is the fastest growing cause of cancer-related deaths in the US; its incidence has almost tripled since 1980. Hepatocellular carcinoma (HCC) is the most prevalent form of liver cancer. Latino/Hispanic (LA) populations are severely affected by HCC compared to Caucasians (CA) with respect to…
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