grant

Revealing environmental chemical exposome in a diverse prenatal population and relationships to maternal and perinatal health (REVEAL)

Organization UNIVERSITY OF CALIFORNIA, SAN FRANCISCOLocation SAN FRANCISCO, UNITED STATESPosted 30 Sept 2016Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY20250-4 weeks old2nd trimester3rd trimesterAccelerationAddressAffectAnalytic ChemistryAnalytical ChemistryBindingBiologicalBiological MarkersBiological MonitoringBirth WeightBloodBlood Reticuloendothelial SystemBlood SampleBlood SerumBlood specimenChemical ExposureChemicalsChronologic Fetal MaturityComplexComputational TechniqueComputational toolkitComputer Software ToolsComputer softwareComputing MethodologiesConcentration measurementDataData AnalysesData AnalysisData BasesDatabasesDevelopmentDiseaseDisorderEnvironmental ExposureEvaluationExposure toFetal AgeGestationGestational AgeGestational DiabetesGestational Diabetes MellitusGoalsHealthHumanLast TrimesterLate pregnancyLatex RubberLeftLinkLow Birth Weight InfantMass Photometry/Spectrum AnalysisMass SpectrometryMass SpectroscopyMass SpectrumMass Spectrum AnalysesMass Spectrum AnalysisMaternal HealthMeasurementMeasuresMethodsMidtrimesterModelingModern ManMolecular InteractionNewborn InfantNewbornsOutcomeOutputPFASParticipantPathway interactionsPatternPhenotypePlasticsPoly-fluoroalkyl substancesPolysiloxanePopulationPopulation HeterogeneityPredispositionPregnancyPregnancy OutcomePregnancy TrimestersPregnancy-Induced DiabetesPregnant WomenPremature BirthPrematurely deliveringPreterm BirthPrevalenceProductionRegulationResearchResolutionRiskRubberSamplingSecond Pregnancy TrimesterSecond TrimesterSerumShotgunsSiloxanesSoftwareSoftware ToolsSourceStaining methodStainsSupercomputingSusceptibilityTechniquesTechnologyThird Pregnancy TrimesterThird Trimesteradvanced analyticsadverse maternal outcomesadverse pregnancy outcomeanalytical methodanalytical toolbio-markersbiologicbiologic markerbiomarkerbiomonitoringchemical groupcomputational methodologycomputational methodscomputational toolboxcomputational toolscomputational toolsetcomputer based methodcomputer methodscomputerized toolscomputing methoddashboarddata basedata integrationdata interpretationdata toolsdevelopmentaldiverse populationsenvironmental chemicalexpectant motherexpectant womenexpecting motherexpecting womenexposed in uteroexposomefat metabolismfetalfetal exposureheterogeneous populationimprovedin utero exposureindividuals who are pregnantintra-uterine environmental exposureintrauterine environmental exposurelipid metabolismlow birth weightlow birthweightmachine learned algorithmmachine learning algorithmmachine learning based algorithmmaternal serummetabolomemetabonomemid-pregnancynatural Rubbernew approachesnewborn childnewborn childrennovelnovel approachesnovel strategiesnovel strategyopen sourcepathwaypeople who are pregnantperfluorinated alkyl substancesperfluoroalkyl substancesperfluoroalkylated substancesperinatal healthperinatal outcomespersonal care productspolyfluorinated alkyl substancespolyfluoroalkyl substancespopulation diversitypregnancy diabetespregnant femalespregnant motherspregnant peoplepregnant populationspremature childbirthpremature deliveryprenatalprenatal exposureprenatally exposedpreterm deliverypreventpreventingpublic health interventionresolutionsshot gunsoftware toolkitstudy populationsuper computingsurfactantthose who are pregnantunbornwomen who are pregnant
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ABSTRACT - Revealing environmental chemical exposome in a diverse prenatal population and
relationships to maternal and perinatal health (REVEAL)

Our renewal application builds on our original R01 by advancing analytical chemistry and computational

techniques to characterize more fully the prenatal chemical exposome and its links to adverse…

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Revealing environmental chemical exposome in a diverse prenatal population and relationships to maternal and perinatal h | Dev Procure