grant
Revealing Cilia Function in the Human Fallopian Tubes
Organization UNIVERSITY OF ARIZONALocation TUCSON, UNITED STATESPosted 12 Aug 2025Deadline 30 Apr 2030
NIHUS FederalResearch GrantFY2025AbscissionAddressAdenomyosisAffectAlgorithmsBody SystemBody TissuesBrightfield AnalysisBrightfield MicroscopyCannulationsCathetersCiliaClinicalCollaborationsComplexComputer softwareConceptionsContrast AgentContrast DrugsContrast MediaDataDevelopmentDevicesDiagnosisDiameterDiseaseDisease ManagementDisorderDisorder ManagementDoppler OCTDysfunctionEctopic PregnancyEmbryoEmbryonicEndoscopesEndoscopyEnvironmentEpitheliumExcisionExtirpationFallopian TubesFeasibility StudiesFemaleFemale Genital SystemFemale HealthFertility DisordersFertilizationFiberFrequenciesFunctional disorderFutureGeneticGenital DisordersHairHistologyHormonalHourHumanIVIS SpectrumCTIVIS imagingIVIS optical imagingIVIS spectral imagingIVIS spectrumIVIS systemImageImpairmentInjuryInstitutionInvestigationLinkLocationMammalian OviductsMapsMeasurementMeasuresMechanicsMenstrual cycleMethodsMiceMice MammalsMicroscopicMicroscopyMiniaturisationsMiniaturizationModern ManMolecularMonitorMovementMucous body substanceMucusMultimodal ImagingMurineMusOCT TomographyObstructionOocytesOperative ProceduresOperative Surgical ProceduresOptical Coherence TomographyOrgan SystemOvocytesPathologyPatientsPelvic Inflammatory DiseasePeriodicalsPhasePhysiologicPhysiologicalPhysiologyPhysiopathologyPilot ProjectsPlayPositionPositioning AttributePre-MenopausePre-implantation Embryo DevelopmentPre-implantation developmentPre-menopausal PeriodPreimplantation Embryo DevelopmentPreimplantation developmentPremenopausalPremenopausal PeriodPremenopauseProcessRadiopaque MediaRemovalReproductionReproductive System DiseaseResearch SpecimenResolutionRoleSalpinxSamplingScreening for Ovarian CancerSideSoftwareSpecimenSpermSpermatozoaStructureSurfaceSurgicalSurgical InterventionsSurgical ProcedureSurgical RemovalSystemTechnologyTestingTimeTissuesTravelTubal ExcisionsUterine TubesUterusVisualizationWomanWomen's Healthbody movementcilium motilityclinical diagnosticsclinical investigationclinical relevanceclinical translationclinically relevantclinically translatablecomparativedesigndesign,build,testdesigningdevelopmentalendometriosisendoscopic imagingexperienceextrauterine pregnancyfemale fertilityfemale genital tractfemale reproductive body systemfemale reproductive organ systemfemale reproductive systemfemale reproductive tractfertility assistancefertility defectfertility interventionsfertility treatmentfertilizationsgenital tractgynecologic body systemgynecologic organ systemhigh resolution imagingimage processingimage-based methodimagerimagingimaging in vivoimaging methodimaging modalityin vivoin vivo imagingin vivo imaging systeminfertility treatmentinjuriesmechanicmechanicalmedical diagnosticmucousmulti-modal imagingmulti-modalitymulti-modality imagingmultimodalitymultimodality imagingnoveloptical Doppler tomographyoptical coherence Doppler tomographyovarian cancer detectionovarian cancer early detectionovarian cancer early screeningoviductpathophysiologypelvic inflammation diseasepelvic inflammation disorderpelvic inflammatory disorderpelvic inflammatory syndromeperiodicperiodicalpilot studypre-menopausalpremenopausal statusprimary infertilityrecruitreproductivereproductive diseasereproductive disorderreproductive system disorderreproductive tractresectionresolutionssafety and feasibilitysalpingectomysocial rolesperm cellstandard of caresubfertilitysurgerytubectomywombwomen's genital tractwomen's reproductive tractzoosperm♀
Description preview
SUMMARY
The overall objective of this study is to advance our understanding of the role motile cilia play in the fallopian
tubes (FTs) and to develop an endoscopic imaging system for in vivo clinical investigation of motile cilia function
in FT pathologies.
The FTs transport oocytes, sperm, embryos, and provide the environment for the complex…
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