grant

Resource Core

Organization VANDERBILT UNIVERSITY MEDICAL CENTERLocation NASHVILLE, UNITED STATESPosted 11 Aug 2025Deadline 31 Jul 2030
NIHUS FederalResearch GrantFY2025(TNF)-α3-indolylacetic acidAIDS VirusAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAlcohol Chemical ClassAlcoholsAppointmentArchivesAssayB cell differentiation factorB cell stimulating factor 2B-Cell Differentiation FactorB-Cell Differentiation Factor-2B-Cell Stimulatory Factor-2BCDFBSF-2BSF2BioassayBioinformaticsBiological AssayBiological MarkersBiological Specimen BanksBiological Substance BanksBiometricsBiometryBiostatisticsBlood PlasmaBlood SerumBlood VesselsCD4 CellsCD4 Positive T LymphocytesCD4 T cellsCD4 helper T cellCD4 lymphocyteCD4+ T-LymphocyteCD4-Positive LymphocytesCachectinCell BodyCellsChemotactic CytokinesClinicalCohort AnalysesCohort AnalysisCohort StudiesCollaborationsCollectionComputer softwareConcurrent StudiesCoupledDataData AnalysesData AnalysisData AnalyticsData BanksData BasesData ReportingData ScienceData Storage and RetrievalDatabanksDatabasesDysfunctionELISAEndocrine Gland SecretionEnsureEnzyme-Linked Immunosorbent AssayEquipmentEquipment and supply inventoriesFlow CytofluorometriesFlow CytofluorometryFlow CytometryFlow MicrofluorimetryFlow MicrofluorometryFunctional MetagenomicsFunctional disorderFundingGC MSGCMSGLP-1Gas-Liquid-Mass Spectrometry ChromatographyGenerationsGlp-1GoalsHIVHPGFHeavy DrinkingHepatocyte-Stimulating FactorHistoryHomologous Chemotactic CytokinesHormonesHuman Immunodeficiency VirusesHybridoma Growth FactorIES cpdIFN-beta 2IFNB2IL-6IL6 ProteinImmuneImmune Cell ActivationImmunesImmunologic SubtypingImmunophenotypingInflammatoryIntercrinesInterleukin-6InventoryInvestigationJointsKynurenineL-TryptophanLAV-HTLV-IIILevotryptophanLogisticsLymphadenopathy-Associated VirusMGI-2Machine LearningMacrophage-Derived TNFMass FragmentographiesMass FragmentographyMass-Gas Chromatography SpectrometryMass-Gas Chromatography Spectrum AnalysisMetagenomicsMethodologyMethodsMonocyte-Derived TNFMultiomic DataMyeloid Differentiation-Inducing ProteinNCI OrganizationNIAAANational Cancer InstituteNational Institute on Alcohol Abuse and AlcoholismOutcomeOutputPBMCPatient outcomePatient-Centered OutcomesPatient-Focused OutcomesPeptidesPeripheral Blood Mononuclear CellPhenotypePhysiopathologyPlasmaPlasma SerumPlasmacytoma Growth FactorPreparationProceduresRecording of previous eventsReproducibilityResearchResearch DesignResearch InstituteResearch ResourcesResourcesReticuloendothelial System, Serum, PlasmaSIS cytokinesSamplingSampling StudiesSerumSoftwareSourceStaining methodStainsStandardizationStatistical Data AnalysesStatistical Data AnalysisStatistical Data InterpretationStudy TypeSystemT-Cell SubsetsT-CellsT-LymphocyteT-Lymphocyte SubsetsT4 CellsT4 LymphocytesTNFTNF ATNF AlphaTNF geneTNF-αTNFATNFαTherapeutic HormoneTryptophanTryptophan MetabolismTryptophan Metabolism PathwayTumor Necrosis FactorTumor Necrosis Factor-alphaUniversitiesVirus-HIVWorkbeta-indoleacetic acidbio-markersbiologic markerbiological specimen archivesbiological specimen repositorybiomarkerbiosample archivebiosample repositorybiospecimen archivebiospecimen bankbiospecimen repositorychemoattractant cytokinechemokinecohortcomputational pipelinescytokinedata acquisitiondata acquisitionsdata basedata depositorydata interpretationdata managementdata repositorydata representationdata representationsdata retrievaldata set repositorydata standardizationdata standardsdata storagedataset repositorydrink heavilyenzyme linked immunoassayexcessive alcohol consumptionexcessive alcohol ingestionexcessive alcohol intakeexcessive drinkingexcessive ethanol ingestionextreme drinkingflow cytophotometryglucagon-like peptide 1heavy alcohol usehistoriesimmune activationindole acetic acidindole-3-acetic acidindoleacetic acidindolyl-3-acetic acidinferential statisticsinterferon beta 2ion trap mass spectrometrymachine based learningmass fragmentometrymetabolism measurementmetabolomicsmetabonomicsmultiple omic datapathophysiologypatient oriented outcomespreparationsrepository infrastructurerepository structureresponsesenescencesenescentspecimen archivespecimen bankspecimen repositorystatistical analysisstudy designsystemic inflammationsystemic inflammatory responsethymus derived lymphocytevascularvascular inflammation
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Description preview

The Resource Core (RC) is comprised of three sub-cores: 1) Metabolomics sub-core, 2) Bioanalytical sub-
core, and 3) Data Science sub-core. The RC will provide a unified analytical platform that is integrated to meet

all the technical needs for data acquisition, data management and analysis and data storage, across all three

projects of the…

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